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The Potential Coexistence of Autoimmune Thyroid Diseases and Pediatric Vulvar Lichen sclerosus

Children
Introduction: Vulvar lichen sclerosus (VLS), a chronic inflammatory skin disorder, often coexists with autoimmune thyroid disease (AITD). VLS presents with subtle symptoms including vulvar itching and discomfort.
Agnieszka Dulska, Jakub Bodziony, Marta Janik, Agnieszka Drosdzol-Cop   +3 more
doaj   +2 more sources

Differential Clinical Signatures of Vulvar Lichen Sclerosus, Lichen Planus, and Chronic Lichen Simplex: A Comparative Study in 1355 Patients [PDF]

Clinical, Cosmetic and Investigational Dermatology
Qiang Hu,1,2,* Kailü Sun,2,* Lin Liu,2 Yuexi He,2,3 Yakun Shao,2 Teng Liu,2 Kun Yang,2 Min Yang,2 Jianmin Chang1,2 1Department of Dermatology, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese ...
Hu Q, Sun K, Liu L, He Y, Shao Y, Liu T, Yang K, Yang M, Chang J   +8 more
doaj   +2 more sources

Study of 138 vulvar lichen sclerosus patients and the malignant risk transformation. [PDF]

Rev Bras Ginecol Obstet
Objective To report the prevalence of malignant transformation of vulvar lichen sclerosus (VLS) and possible risk factors. Methods This is a cohort study with data analysis from medical records of 138 patients with histological diagnosis of VLS ...
Vasconcellos BO, Fialho SCAV, Guimarães ICCDV, Martins CAO, de Moraes JR, Zanine RM, Guimarães JCC, Pérez-López F.   +7 more
europepmc   +2 more sources

Characterization and therapeutic strategies for refractory vulvar lichen sclerosus: an 8-year single-center retrospective study and current evidence synthesis

Journal of Dermatological Treatment
Objective Untreated vulvar lichen sclerosus (VLS) can lead to irreversible anatomical changes and increase malignancy risk. Some patients show poor response to standard treatments, resulting in refractory cases (RVLS).Methods To explore risk factors ...
Lin Liu, Jun Cui, Kailv Sun, Min Yang, Qiuli Zhang, Kun Yang, Chang Jianmin   +6 more
doaj   +2 more sources

Dermoscopy for monitoring therapeutic response to hybrid cooperative complexes of hyaluronic acid in women with vulvar lichen sclerosus and atrophy [PDF]

Frontiers in Medicine
IntroductionVulvar Lichen Sclerosus (VLS) is a chronic relapsing inflammatory disease involving the anogenital region, resulting in vulvar atrophy and distressing symptoms.
Giulio Rizzetto, Edoardo De Simoni, Alessandro Borghi, Elisa Molinelli, Marinella Tedesco, Emilia Migliano, Corrado Tagliati, Monica Corazza, Franco Grimolizzi, Gilberto Bellia, Camilla Barduagni, Annamaria Offidani, Oriana Simonetti   +12 more
doaj   +2 more sources

Lack of oral involvement in a large cohort of women with vulvar lichen sclerosus - a multicenter prospective study. [PDF]

J Dtsch Dermatol Ges
Background and Objectives: We assessed the prevalence of oral lichen sclerosus in a cohort of women affected with vulvar lichen sclerosus (VLS).
Corazza M, Salvini C, Gaspari V, Simonetti O, Schettini N, de Magnis A, Rapparini L, Rizzetto G, Misciali C, Marzola E, Borghi A.   +10 more
europepmc   +2 more sources

First use of cord blood platelet-rich plasma in the treatment of vulvar lichen sclerosus: a preliminary study towards a randomized controlled trial. [PDF]

Blood Transfus
Background Although topical corticosteroids (TCS) represent first-line treatment for vulvar lichen sclerosus (VLS) and as such should be prescribed to all women at time of diagnosis, approximately 30% of patients do not experience complete symptom ...
Boero V, Caia C, Cetera GE, Pesce E, Uccello S, Villa S, Montemurro T, Mykhailova L, Merli CEM, Monti E, Filippi F, Vercellini P, Prati D.   +12 more
europepmc   +2 more sources

Efficacy of Fractional CO₂ Laser Therapy in Improving Symptoms and Quality of Life in Women with Refractory Vulvar Lichen Sclerosus: A Prospective Observational Study. [PDF]

Life (Basel)
Lichen sclerosus (LS) is a chronic inflammatory condition predominantly affecting the anogenital region of postmenopausal women. It is associated with considerable aesthetic and functional impairments and an increased risk of squamous cell carcinoma ...
Gil-Villalba A, Ayén-Rodríguez Á, Naranjo-Díaz MJ, Linares-González L, Ruiz-Villaverde R.   +4 more
europepmc   +2 more sources

Outcome Measures in Adult Vulvar Lichen Sclerosus:A Case Series of Women Diagnosed as Juveniles [PDF]

Journal of Lower Genital Tract Disease
OBJECTIVES: Studies on the consequences of juvenile vulvar lichen sclerosus (JVLS) in adulthood are limited. A number of measuring tools are available for analyzing adult vulvar lichen sclerosus (VLS), but these have not been applied in studies on JVLS ...
Burger, Curt W., Morrel, Beth, Pasmans, Suzanne G.M.A., Ten Kate-Booij, Marianne J., van der Avoort, Irene A.M., van Dijk, Charlotte, van Hees, Colette L.M., Wigny, Kiki M.G.J.   +7 more
core   +3 more sources

Outcome Measures in Adult Vulvar Lichen Sclerosus:A Systematic Review [PDF]

Journal of Lower Genital Tract Disease
Objectives:Core outcome domains (CODs) for treatment of adult vulvar lichen sclerosus (VLS) have recently been established through a Delphi study. A number of measuring tools are available for evaluating VLS.
Bramer, Wichor M., Burger, Curt W., Morrel, Beth, Pasmans, Suzanne G.M.A., Ten Kate-Booij, Marianne J., Van Der Avoort, Irene A.M., Van Dijk, Charlotte   +6 more
core   +3 more sources