Results 21 to 30 of about 1,913 (181)

Characterization and therapeutic strategies for refractory vulvar lichen sclerosus: an 8-year single-center retrospective study and current evidence synthesis

open access: diamondJournal of Dermatological Treatment
Objective Untreated vulvar lichen sclerosus (VLS) can lead to irreversible anatomical changes and increase malignancy risk. Some patients show poor response to standard treatments, resulting in refractory cases (RVLS).Methods To explore risk factors ...
Lin Liu   +6 more
doaj   +2 more sources

TGF-β drives myofibroblast activation and inflammatory mediator production in vulvar lichen sclerosus. [PDF]

open access: goldAJOG Glob Rep
Fischer SA   +10 more
europepmc   +2 more sources

<p>Vulvar Lichen Sclerosus: Current Perspectives</p>

open access: goldInternational Journal of Women's Health, 2020
Vulvar lichen sclerosus (LS) is a chronic, inflammatory dermatosis that may lead to scarring of the vulva and sexual dysfunction. LS affects women of all ages and often goes unrecognized and underreported. Uncertainty continues to exist around its pathogenesis, histologic diagnosis, and treatment.
Jill M. Krapf   +3 more
openalex   +6 more sources

Quality of life and its influencing factors in patients with vulvar lichen sclerosus: Based on a questionnaire survey of 198 adult women

open access: yesPifu-xingbing zhenliaoxue zazhi, 2022
Objective To investigate the status of quality of life in adult women patients with vulvar lichen sclerosus and its influencing factors, and to provide evidence for optimizing their quality of life.
Jinghui SONG   +4 more
doaj   +1 more source

Pediatric Vulvar Lichen Sclerosus-A Review of the Literature. [PDF]

open access: yesInt J Environ Res Public Health, 2021
Vulvar lichen sclerosus (VLS) is a chronic inflammatory condition affecting the anogenital region, which may present in a prepubertal or adolescent patient. The most popular theories are its autoimmune and genetic conditioning, although theories concerning hormonal and infectious etiology have also been raised.
Orszulak D   +6 more
europepmc   +6 more sources

Vulvar dermatoses: a cross-sectional 5-year study. Experience in a specialized vulvar unit [PDF]

open access: yesAnais Brasileiros de Dermatologia, 2022
Background: Vulvar diseases are common in the general population and have a negative impact on the quality of life. Objectives: To describe our experience as dermatologists in the management of vulvar dermatosis consultations.
Fernando García-Souto   +7 more
doaj   +1 more source

Immune pathogenesis and immune therapy of a sclerosing variant of vulvar lichen sclerosus: a prospective cohort study

open access: yesКубанский научный медицинский вестник, 2023
Background. Today, no unified clinical classification of vulvar lichen sclerosus is registered (is yet to be registered?). Isolation of pathogenetically and clinically different variants of its course enable new approaches to the treatment to be ...
E. V. Kolesnikova   +3 more
doaj   +1 more source

Dermoscopic features of vulvar lichen sclerosus in children: an analysis of 41 cases

open access: yesPifu-xingbing zhenliaoxue zazhi, 2023
Objective To analyze dermoscopic features of vulvar lichen sclerosus in children. Methods The dermoscopic images of vular lichen sclerosus were retrospectively analyzed in 41 children who were treated at our department.
Yuanyuan CHAI   +4 more
doaj   +1 more source

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