OBJECTIVES: The vulva is the primary site affected in lichen sclerosus, a chronic dermatosis in women that is histologically characterized by a zone of collagen remodeling in the superior dermis. The normal physiological properties of the vulva depend on
Charles A.P. Godoy +7 more
doaj +1 more source
Predicting the development of vulvar lichen sclerosus
Relevance. The issue of timely diagnosis and treatment of vulvar lichen sclerosus has become especially acute in recent years due to the “rejuvenation” of the disease and the risk of its malignancy.
Ekaterina V. Kolesnikova +3 more
doaj +1 more source
Vulvar Pruritus: A Review of Clinical Associations, Pathophysiology and Therapeutic Management
Vulvar pruritus is an unpleasant sensation and frequent symptom associated with many dermatologic conditions, including infectious, inflammatory and neoplastic dermatoses affecting the female genitalia.
Haya S. Raef +2 more
doaj +1 more source
High frequency of loss of heterozygosity in vulval intraepithelial neoplasia (VIN) is associated with invasive vulval squamous cell carcinoma (VSCC) [PDF]
Vulval intraepithelial neoplasia (VIN) is thought to be the premalignant phase of human papillomavirus (HPV)-associated vulval squamous cell carcinoma (VSCC).
Abbou, M. (Mustaffa) +6 more
core +2 more sources
Platelet-Rich Plasma (PRP) and Adipose-Derived Stem Cell (ADSC) Therapy in the Treatment of Genital Lichen Sclerosus: A Comprehensive Review [PDF]
Lichen sclerosus (LS) is a chronic inflammatory dermatosis mostly localized in the genital area, characterized by vulvar alterations that can severely impact a patient's quality of life.
Condorelli A. +6 more
core +1 more source
Human papillomavirus-associated increase in p16INK4A expression in penile lichen sclerosus and squamous cell carcinoma [PDF]
Re-use of this article is permitted in accordance with the Creative Commons Deed, Attribution 2·5, which does not permit commercial exploitationBackground: Human papillomaviruses (HPVs) are sexually transmitted human carcinogens that may play a role in ...
Baithun +34 more
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Lichen sclerosus is a chronic inflammatory condition of unknown etiology that affects the genital and extragenital skin, which can lead to sexual dysfunction and has been associated with vulvar cancer.
Oluwatobiloba A. Taylor +9 more
doaj +1 more source
Genital Skin Diseases and Their Expression in Sexual Functionality [PDF]
Sexual functionality acts as an important function of the individual, acting both physically and mentally to create a state of well-being and permitting procreation.
Albu, Gabriela +3 more
core +2 more sources
Dermoscopic and reflectance confocal microscopy features of two cases of vulvar basal cell carcinoma [PDF]
Basal cell carcinoma (BCC) is the most common malignant skin cancer. Its genital localization is rare, and the diagnosis in this site could be challenging.
Cinotti, Elisa +5 more
core +2 more sources
Menina de cinco anos com antecedentes de obstipação e enurese noturna primária, medicada com desmopressina. Referenciada pelo médico assistente à consulta de Pediatria por despigmentação e erosões vulvares associada a prurido intenso, com dois meses de ...
Carvalho, Sónia +5 more
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