High frequency of loss of heterozygosity in vulval intraepithelial neoplasia (VIN) is associated with invasive vulval squamous cell carcinoma (VSCC) [PDF]
Vulval intraepithelial neoplasia (VIN) is thought to be the premalignant phase of human papillomavirus (HPV)-associated vulval squamous cell carcinoma (VSCC).
Abbou, M. (Mustaffa) +6 more
core +6 more sources
Unexpected high frequency of genital involvement in women with clinical and hostological features of oral lichen planus [PDF]
The main aims of this cross-sectional study were: (i) to assess the frequency of genital (vulval) lichen planus (VLP) and vulval lichen sclerosus (VLS) in women affected with oral lichen planus (OLP), regardless of the genital symptoms reported; and (ii)
BELFIORE, P +6 more
core +1 more source
Vulvitis circumscripta plasmacellularis in pre-existing lichen sclerosus
Vulvitis circumscripta plasmacellularis (VCP) is a rare, benign vulvar disorder that presents with erythematous patches and erosions. Patients with VCP usually experience vulvodynia, pruritus, or dyspareunia, which may cause severe discomfort.
Han Su Kim +4 more
doaj +1 more source
Conscious sedation with inhaled 50% nitrous oxide/oxygen premix in photodynamic therapy sessions for vulvar lichen sclerosus treatment [PDF]
Photodynamic therapy has been described as an effective therapeutic option in selected cases of anogenital lichen sclerosus that are refractory to first-line treatments.
Joana Cabete, Sara Campos, Sara Lestre
doaj +1 more source
The vulvar microbiome in lichen sclerosus and high-grade intraepithelial lesions
BackgroundThe role of the vulvar microbiome in the development of (pre)malignant vulvar disease is scarcely investigated. The aim of this exploratory study was to analyze vulvar microbiome composition in lichen sclerosus (LS) and vulvar high-grade ...
Lisa Pagan +21 more
doaj +1 more source
Diagnostic criteria for erosive lichen planus affecting the vulva: an international electronic-Delphi consensus exercise [PDF]
Background: There is no defined set of criteria for diagnosing erosive lichen planus affecting the vulva (ELPV) and there is geographical variation in management.
Leighton, Paul +3 more
core +2 more sources
Etiology, Clinical Features, and Diagnosis of Vulvar Lichen Sclerosus: A Scoping Review
Objective. Vulvar lichen sclerosus (VLS) is a chronic inflammatory disorder, which affects women of all ages. With numerous controversies as regards to the nomenclature, diagnosis and its association with neoplastic conditions, we decided to conduct a ...
Nilanchali Singh, Prafull Ghatage
doaj +1 more source
Introduction: The vulva is an external female genital organ with complex anatomy and histology. In postmenopausal women, this region is at particular risk of different types of conditions known as dermatoses.
Michał Migda +3 more
doaj +1 more source
OBJECTIVES: The vulva is the primary site affected in lichen sclerosus, a chronic dermatosis in women that is histologically characterized by a zone of collagen remodeling in the superior dermis. The normal physiological properties of the vulva depend on
Charles A.P. Godoy +7 more
doaj +1 more source
Vulvar Pruritus: A Review of Clinical Associations, Pathophysiology and Therapeutic Management
Vulvar pruritus is an unpleasant sensation and frequent symptom associated with many dermatologic conditions, including infectious, inflammatory and neoplastic dermatoses affecting the female genitalia.
Haya S. Raef +2 more
doaj +1 more source

