Results 111 to 120 of about 311,018 (229)

Proximal-type epithelioid sarcoma of vulva – Case series of a rare tumor

open access: yesGynecologic Oncology Reports, 2022
Epithelioid sarcoma (ES) is rare and aggressive soft tissue neoplasm characterized by tumor cells showing epithelioid morphology and immunohistochemically, characteristic loss of INI1/ SMARCB1 in most cases.
Biswajit Dash   +4 more
doaj  

The impact of local symptoms on health‐related quality of life in vulvar cancer survivors—A nationwide prospective study

open access: yesActa Obstetricia et Gynecologica Scandinavica, Volume 104, Issue 8, Page 1517-1529, August 2025.
In this Swedish nationwide study, women reported a high prevalence of local vulvar symptoms which improved after treatment and during follow‐up. Severe and persisting vulvar symptoms were associated with a significant deterioration in physical, emotional, role, social, and cognitive functioning.
Diana Zach   +8 more
wiley   +1 more source

Retrospective clinical and molecular characterisation of patients with penile intraepithelial neoplasia

open access: yesBJU International, Volume 136, Issue 2, Page 280-288, August 2025.
Objectives To provide the first comprehensive molecular characterisation of penile intraepithelial neoplasia (PeIN) and to define the molecular alterations and clinical parameters associated with recurrence in order to enhance our ability to manage this disease.
Sara Kaczor Elbæk   +6 more
wiley   +1 more source

Correlating p53 immunostaining patterns with somatic TP53 mutation and functional properties of mutant p53 in triple‐negative breast cancer

open access: yesHistopathology, Volume 87, Issue 2, Page 299-309, August 2025.
This study introduces newly defined criteria for interpreting p53 IHC expression in triple‐negative breast cancer. These criteria could enable the prediction of TP53 mutation types and their functional implications, providing valuable insights for future clinical research and potentially improving stratification of treatment options for patients.
Meejeong Kim   +7 more
wiley   +1 more source

The TP53 tumor suppressor gene: From molecular biology to clinical investigations

open access: yesJournal of Internal Medicine, Volume 298, Issue 2, Page 78-96, August 2025.
Abstract Extensively studied over the past four decades, the TP53 gene has emerged as a pivotal watchman in cellular defense and a key factor in cancer biology. TP53 is the most frequently mutated gene in human malignancies, 50% of which carry alterations to it.
Panagiotis Baliakas, Thierry Soussi
wiley   +1 more source

Epithelioid fibrous histiocytoma of the vulva: Report of a case with next-generation sequencing analysis

open access: yesHuman Pathology: Case Reports, 2020
Epithelioid fibrous histiocytoma (EFH), also known as epithelioid cell histiocytoma (ECH), is an uncommon benign cutaneous mesenchymal neoplasm that typically occurs in the limbs and consistently harbors ALK gene rearrangements.
Lu Zhao   +5 more
doaj  

Case of Metastatic Canine Transmissible Venereal Tumor in a Dog: Clinical and Cytological Evaluation

open access: yesMedia Kedokteran Hewan
Canine transmissible venereal tumor (TVT) is a naturally occurring, transmissible neoplasm primarily affecting the genitalia in dogs. Though generally benign, it can rarely metastasize to other body parts.
Olanrewaju Samuel Olaifa   +8 more
doaj   +1 more source

Aggressive angiomyxoma of the vulva: dramatic response to gonadotropin-releasing hormone agonist therapy

open access: yesJournal of Research in Medical Sciences, 2007
<p>Aggressive angiomyxoma is a rare soft tissue neoplasm that usually arises within the perineum. It often occurs as a vulvar mass and clinically simulates a Bartholin&#39;s gland cyst.
Azar Danesh, Mohammad Hossein Sanei
doaj  

Giant vulvo-abdominal aggressive angiomyxomas, report of two cases

open access: yesRevista Médica del Hospital General de México, 2018
Aggressive angiomyxoma is a rare type of soft tissue tumour. It has traditionally been described as a low-grade myxomatous neoplasm of the vulvovaginal, perineal and pelvic regions in women, and has a high rate of recurrence because of its infiltrative ...
A. Cañavera-Constantino   +3 more
doaj  

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