Results 31 to 40 of about 12,789 (247)

Identification of human papillomavirus DNA in cutaneous lesions of Cowden syndrome [PDF]

open access: yes, 2003
Background: Cowden syndrome (CS) or multiple hamartoma syndrome is a cancer-associated genodermatosis inherited in an autosomal dominant pattern. One of the diagnostic criteria is facial papules which are felt to be trichilemmomas, benign hair follicle ...
Burgdorf, Walter H. C.   +4 more
core   +1 more source

Background and precancerous processes in the vulva and vagina: etiology, pathogenesis, diagnosis and treatment

open access: yesАкушерство, гинекология и репродукция, 2019
Leukoplakia, kraurosis and pointed condylomas (papillomas) of the vulva represent the group of background benign vulvar diseases. Vulvar and vaginal intraepithelial neoplasms are classified as premalignant conditions.
A. G. Solopova   +5 more
doaj   +1 more source

Erythema nodosum induced by oral isotretinoin in a patient with condylomata acuminata [PDF]

open access: yes, 2020
Erythema nodosum (EN) is a form of septal panniculitis, which is believed to represent a delayed hypersensitivity reaction activated by infectious agents, drugs, granulomatous and autoimmune diseases, pregnancy, and malignancies.
Badavanis, George   +4 more
core  

Lymphoepithelioma-like carcinoma of the vulva, an underrecognized entity? Case report with a single inguinal micrometastasis detected by sentinel node technique [PDF]

open access: yes, 2011
This report describes an unusual EBV-negative lymphoepithelioma-like carcinoma of the vulva in a 73-year-old patient. The lesion was localised at the right minor labium and was resected by partial vulvectomy.
Hans Bösmüller   +5 more
core   +2 more sources

Progressing Vulvar Melanoma Caused by Instability in cKIT Juxtamembrane Domain: A Case Report and Review of Literature

open access: yesCurrent Oncology, 2022
In order to identify the molecular pathways governing melanoma and track its progression, the next-generation sequencing (NGS) approach and targeted sequencing of cancer genes were employed.
Monika Englert-Golon   +9 more
doaj   +1 more source

Descriptive epidemiology of vulvar and vaginal cancers in Vaud, Switzerland, 1974-1994 [PDF]

open access: yes, 2017
Background: To analyse trends in incidence, survival and risk of second neoplasms following vaginal and vulvar cancers using data collected by the Swiss Cancer Registry of Vaud over the 21-year period 1974-1994.
La Vecchia, C.   +2 more
core  

Cowden syndrome - Diagnostic skin signs [PDF]

open access: yes, 2001
Cowden syndrome is a rare autosomal dominant familial cancer syndrome with a high risk of breast cancer. The most important clinical features include carcinomas of the breast and thyroid, and hamartomatous polyps of the gastrointestinal tract.
Burgdorf, Walter H. C.   +2 more
core   +1 more source

ECM‐Stiffness Mediated Persistent Fibroblast Activation Requires Integrin and Formin Dependent Chromatin Remodeling

open access: yesAdvanced Science, EarlyView.
Prolonged exposure to stiff extracellular matrix drives cancer‐associated fibroblasts into a persistently activated myofibroblast state. Two parallel pathways are identified: β1 integrin activation smoothens the nuclear lamina to reduce lamin–chromatin contacts, while the formin mDia2 regulates nuclear actin to alter chromatin organization.
Swathi Packirisamy   +4 more
wiley   +1 more source

Periorbital syringomas - excision with Castroviejo scissors: experience in 38 patients and literature review [PDF]

open access: yes, 2006
BACKGROUND: Syringomas are benign adnexal tumors from intraepidermal eccrine ducts, treated by diverse surgical modalities with variable results. OBJECTIVES: 1.
Bagatin, Edileia   +2 more
core   +3 more sources

Selenium‐Based Nanoplatforms: An Emerging Theranostic Paradigm for Gynecological Cancers

open access: yesAdvanced Science, EarlyView.
This reivew summarizes Selenium as a multifunctional anticancer regulator in gynecological cancers. It reduces tumor risk, enhances therapeutic efficacy, and reduces treatment toxicity. Selenium also overcomes chemoraditherapy resistance, improving overall treatment outcomes. ABSTRACT Gynecological cancers present significant therapeutic challenges due
Hejing Liu   +9 more
wiley   +1 more source

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