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Inflammation, lipids, and pain in vulvar disease

Pharmacology & Therapeutics, 2023
Localized provoked vulvodynia (LPV) affects ∼14 million people in the US (9% of women), destroying lives and relationships. LPV is characterized by chronic pain (>3 months) upon touch to the vulvar vestibule, which surrounds the vaginal opening. Many patients go months or years without a diagnosis.
Megan L, Falsetta   +2 more
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Management of vulvar pain

Dermatologic Therapy, 2004
Vulvodynia is a frequently used medical term that literally means "vulvar pain". Therefore, vulvodynia is a symptom, not a disease. The term itself indicates a variety of unpleasant chronic vulvar sensations, including burning, rawness, soreness, irritation, sensitivity, and formication. This may or may not include dyspareunia.
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Vulvar Pain

Journal of Lower Genital Tract Disease, 1997
In 1975, the International Society for the Study of Vulvar Disease recommended the term vulvodynia to describe vulvar pain regardless of its cause. For most clinicians, vulvar pain is, to say the least, confusing. It is not one disease but, in most cases, the manifestation of several diseases often erroneously lumped together because they are ...
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Vulvar Pain Syndromes: Vestibulodynia

Journal of Midwifery & Women's Health, 2006
ABSTRACTChronic pain anywhere on the body can be debilitating and demoralizing. When the pain is associated with sexuality, it can erode self‐esteem and diminish relationships. Vestibulodynia (pain in the vulvar vestibule) is poorly understood and presents a clinical challenge to the provider.
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Iatrogenic Vulvar Pain

2017
Physicians and healthcare providers (HCPs) can contribute to vulvar pain with different pathophysiologic pathways and responsibilities. They seem to be often unaware of a dramatic truth, valid in every field of medicine: doctors can be cofactors in the pathogenesis of a disease (Graziottin 2006; Norian and Stratton 2008; Esparaz et al.
Alessandra Graziottin, Filippo Murina
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Vulvar pilonidal sinuses: treatment of a rare cause of vulvar pain

Archives of Gynecology and Obstetrics, 2008
It is hoped that if cases of vulvar pilonidal sinus (PS) are known to readers of this article, they will be called to the writer's attention and that further studies of the origin and cause of these anterior pathologic developments will result. A delay in diagnosis and treatment of this relatively harmless condition can lead to complications like ...
Hasan, Kafali   +3 more
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The role of vulvar skin biopsy in the evaluation of chronic vulvar pain

American Journal of Obstetrics and Gynecology, 2008
Sixty-one percent of refractory vulvodynia patients evaluated in a tertiary care vulvovaginal clinic had clinically relevant dermatoses based on dermatopathologist-analyzed vulvar biopsy including: lichen sclerosus, allergic/irritant dermatitis, lichen planus, and other inflammatory or neoplastic dermatoses. Given the frequency of dermatologic disease,
Anneli R, Bowen   +5 more
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[Vulvar Pain].

Therapeutische Umschau. Revue therapeutique, 2019
Vulvar Pain Abstract. During their lifetime, many women experience vulvar and / or vaginal pain. The reasons of those pains or discomforts can be multiple and sometimes hard to identify and therefore difficult to treat. Besides organic causes such as infections, inflammations, changes after operations and others we can find complex conditions such as ...
Laurent, Hastert, Brigitte, Frey Tirri
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Vulvar Pain in Adolescents

2017
Adolescence is the life period when vulvar pain of various etiologies, and specifically vestibulodynia/vulvodynia, begins to be diagnosed, investigated, and treated (Bachmann et al. 2006; Clare and Yeh 2011; Graziottin and Murina 2011; Reed et al. 2014).
Alessandra Graziottin, Filippo Murina
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Epidemiology of Vulvar Pain

2017
Vulvar pain is a very common problem that affects women of all age groups. Too often, women endure pain and sexual dysfunction for years without an adequate definitive diagnosis. They are desperate for help, looking for every type of medical and alternative treatment and regularly self-treat, wasting a lot of money a year in disappointing/frustrating ...
Alessandra Graziottin, Filippo Murina
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