Results 131 to 140 of about 6,941 (175)

Lymphovascular invasion and p16 expression are independent prognostic factors in stage I vulvar squamous cell carcinoma. [PDF]

Virchows Arch
Davidson B, Skeie-Jensen T, Holth A, Lindemann K, Toralba Barrameda AM, Lie AK, Wang Y.   +6 more
europepmc   +1 more source

Phase II Trial of Cisplatin, Gemcitabine, and Intensity-Modulated Radiation Therapy for Locally Advanced Vulvar Squamous Cell Carcinoma: NRG Oncology/GOG Study 279. [PDF]

J Clin Oncol
Horowitz NS, Deng W, Peterson I, Mannel RS, Thompson S, Lokich E, Myers T, Hanjani P, O'Malley DM, Chung KY, Miller DS, Ueland FR, Dizon DS, Miller A, Mayadev JS, Leath CA, Monk BJ.   +16 more
europepmc   +1 more source

Prognostic value of HPV-PCR, p16 and p53 immunohistochemical status on local recurrence rate and survival in patients with vulvar squamous cell carcinoma. [PDF]

Virchows Arch
Pouwer AW, Te Grootenhuis NC, Hinten F, de Bock GH, van der Zee AGJ, Melchers WJG, Oonk MHM, de Hullu JA, Hollema H, Bulten J.   +9 more
europepmc   +1 more source

Definitive chemoradiation in vulvar squamous cell carcinoma: outcome and toxicity from an observational multicenter Italian study on vulvar cancer (OLDLADY 1.1). [PDF]

Radiol Med
Macchia G, Lancellotta V, Ferioli M, Casà C, Pezzulla D, Pappalardi B, Laliscia C, Ippolito E, Di Muzio J, Huscher A, Tortoreto F, Boccardi M, Lazzari R, Perrone AM, Raspagliesi F, Gadducci A, Garganese G, Fragomeni SM, Ferrandina G, Morganti AG, Gambacorta MA, Tagliaferri L.   +21 more
europepmc   +1 more source

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Putative precancerous lesions of vulvar squamous cell carcinoma

Seminars in Diagnostic Pathology, 2021
Precursor lesions of vulvar squamous cell carcinoma (VSCC) can be divided into two major biologic and prognostic groups: HPV-associated and HPV-independent VSCC. These two pathways are categorized as usual vulvar intraepithelial neoplasia (uVIN) with progression to basaloid or warty VSCC and differentiated vulvar intraepithelial neoplasia (dVIN) with ...
Anne M Mills
exaly   +3 more sources

Margin status revisited in vulvar squamous cell carcinoma [PDF]

Gynecologic Oncology, 2019
To determine the incidence of local recurrence of vulvar squamous cell carcinoma in relation to tumor- and/or precursor lesion free pathologic margins.Consecutive patients with primary vulvar squamous cell carcinoma surgically treated in two Dutch expert centers between 2000 and 2010 were included.
Johan Bulten, Geertruida H. de Bock, Anne-Floor W Pouwer   +2 more
exaly   +5 more sources

Vulvar squamous cell carcinoma

Expert Review of Obstetrics and Gynecology, 2009
Vulvar squamous cell carcinomas account for 90% of all vulvar cancers and originate following two different pathways. Approximately 20% of all vulvar squamous cell carcinomas are caused by an infection with high-risk human papillomavirus. It has been hypothesized that most of these vulvar cancers may be prevented by the recently introduced human ...
Hedwig P van de Nieuwenhof
exaly   +2 more sources

Genomic characterization of vulvar squamous cell carcinoma

Gynecologic Oncology, 2020
Despite increasing incidence, vulvar squamous cell carcinoma (VSCC) is still a rare disease. Until now, two etiological pathways have been described: a high-risk human papillomavirus (HPV)-dependent route and an HPV-independent pathway often associated with lichen sclerosus.
Katharina, Prieske, Malik, Alawi, Leticia, Oliveira-Ferrer, Anna, Jaeger, Kathrin, Eylmann, Eike, Burandt, Barbara, Schmalfeldt, Simon A, Joosse, Linn, Woelber   +8 more
openaire   +2 more sources

Langerhans cells in vulvar lichen sclerosus and vulvar squamous cell carcinoma

Archivum Immunologiae et Therapiae Experimentalis, 2006
Langerhans cells (LCs), specializing in antigen presentation, are a very important part of the skin immune system (SIS).Skin biopsies from 22 women with vulvar lichen sclerosus (LS): 15 patients with early and 7 with the late stage of the disease, were evaluated. Five women with vulvar squamous cell carcinoma (SCC) were also examined. The control group
Helena, Rotsztejn, Ewa, Trznadel-Budźko, Dorota, Jesionek-Kupnicka   +2 more
openaire   +2 more sources

Vulvar squamous cell carcinoma and lichen sclerosus

Australasian Journal of Dermatology, 1997
There are two clinicopathological types of vulvar squamous cell carcinoma, human papillomavirus (HPV)-positive and HPV-negative, which can be distinguished to some degree on routine histology. Human papillomavirus-positive carcinomas account for one-quarter to one-third of cases, occur in women on average 20 years younger than in HPV-negative, and are ...
J P, Scurry, K, Vanin
openaire   +2 more sources