Results 11 to 20 of about 6,941 (175)

The Genomic Landscape of Vulvar Squamous Cell Carcinoma. [PDF]

Int J Gynecol Pathol, 2023
Vulvar squamous cell cancer (VSC) accounts for 90% of vulvar cancers. Next-generation sequencing studies of VSC imply human papillomavirus (HPV) and p53 status play separate roles in carcinogenesis and prognosis. We sought to describe the genomic landscape and analyze the immunologic profiles of VSC with respect to HPV and p53 status.
Corey L, Wallbillich JJ, Wu S, Farrell A, Hodges K, Xiu J, Nabhan C, Guastella A, Kheil M, Gogoi R, Winer I, Bandyopadhyay S, Huang M, Jones N, Wilhite A, Karnezis A, Thaker P, Herzog TJ, Oberley M, Korn WM, Vezina A, Morris R, Ali-Fehmi R.   +22 more
europepmc   +5 more sources

An integrated model for prognosis in vulvar squamous cell carcinoma. [PDF]

BMC Cancer, 2023
Abstract Background Vulvar squamous cell carcinoma (VSCC) is a relatively rare gynecologic cancer. Unlike cervical squamous cell carcinoma (CSCC), in which nearly all cases are caused by HPV infection, most VSCCs are HPV-independent. Patients with VSCC also have worse overall survival (OS) than those with CSCC.
Zhang T, Zhu Y, Luo J, Li J, Niu S, Chen H, Zhou F.   +6 more
europepmc   +4 more sources

Recurrence of vulvar squamous cell carcinoma as an undifferentiated sarcomatoid carcinoma [PDF]

International Journal of Gynecological Cancer, 2021
In November 2019, a 75 year-old woman with a history of diabetes mellitus and major depression with psychotic features underwent a radical vulvectomy, including the resection of the external meatus of the urethra and the distal third of the vagina, for a well-differentiated infiltrating ...
Comerio, Chiara, Jaconi, Marta, Zambetti, Benedetta, Paderno, Mariachiara, Valente, Maria Gabriella, Buda, Alessandro   +5 more
openaire   +2 more sources

Fibrillary Glomerulonephritis in a Patient With Vulvar Squamous Cell Carcinoma. [PDF]

Cureus, 2023
Fibrillary glomerulonephritis is a rare condition characterized by glomerular accumulation of non-branching fibrils, leading to hematuria, proteinuria, and hypertension. It is often associated with malignancy but has no known cause. A 66-year-old Caucasian female with a history of vulvar squamous cell carcinoma presented with one month of painless ...
Jagadish A, Vedantam V, Vedantam N, Magacha HM.   +3 more
europepmc   +3 more sources

Vulvar Adenoid Cystic Carcinoma with Squamous Cell Carcinoma Component

The Kurume Medical Journal, 2022
Adenoid cystic carcinoma (ACC) is a major histological type of salivary gland cancer but an uncommon form of vulvar cancer. Salivary gland ACC occasionally dedifferentiates into high-grade carcinoma, resulting in poor prognoses. The dedifferentiated component is usually a poorly differentiated cribriform or solid carcinoma, whereas squamous cell ...
HAN, AYA, KATO, SEIYA, MORINAGA, KEIGO, IZUMI, MIKI, KIYOKAWA, KENSUKE   +4 more
openaire   +2 more sources

The Vulvar Immunohistochemical Panel (VIP) Project: Molecular Profiles of Vulvar Squamous Cell Carcinoma [PDF]

Cancers, 2021
Introduction: The study’s aim was to investigate the immunohistochemical (IHC) expression of biological markers as potential prognostic/therapeutic factors in vulvar squamous cell carcinoma (VSCC). Methodology: A series of 101 patients surgically treated at our center from 2016 to 2020 were retrospectively enrolled: 53 node-negative (Group A) and 48 ...
Garganese G., Inzani F., Fragomeni S. M., Mantovani G., Corte L. D., Piermattei A., Santoro A., Angelico G., Giaco L., Corrado G., Fagotti A., Zannoni G. F., Scambia G.   +12 more
openaire   +4 more sources

Normalizers for microRNA quantification in plasma of patients with vulvar intraepithelial neoplasia lesions and vulvar carcinoma

Tumor Biology, 2017
The role of circulating microRNAs as a promising tool for diagnosing cancer and monitoring anticancer therapies has been widely studied in the past decades.
Kamil Zalewski, Marcin Misiek, Artur Kowalik, Elwira Bakuła-Zalewska, Janusz Kopczyński, Aleksandra Zielińska, Mariusz Bidziński, Jakub Radziszewski, Stanisław Góźdź, Magdalena Kowalewska   +9 more
doaj   +1 more source

Exploring Differentially Methylated Genes in Vulvar Squamous Cell Carcinoma [PDF]

Cancers, 2021
DNA methylation is the most widely studied mechanism of epigenetic modification, which can influence gene expression without alterations in DNA sequences. Aberrations in DNA methylation are known to play a role in carcinogenesis, and methylation profiling has enabled the identification of biomarkers of potential clinical interest for several cancers ...
Shatavisha Dasgupta, Patricia C. Ewing-Graham, Sigrid M. A. Swagemakers, Thierry P. P. van den Bosch, Peggy N. Atmodimedjo, Michael M. P. J. Verbiest, Marit de Haan, Helena C. van Doorn, Peter J. van der Spek, Senada Koljenović, Folkert J. van Kemenade   +10 more
openaire   +2 more sources

Pilomatrix carcinoma of the vulva

Gynecologic Oncology Reports, 2016
Background: Pilomatrix carcinomas are rare, frequently occurring in older male patients. We report a case of vulvar pilomatrix carcinoma in a 30-year-old woman, the second known reported case occurring on the external genitalia.
Mihae Song, Marina Chekmareva, Gloria Bachmann, Darlene Gibbon   +3 more
doaj   +1 more source

Treatment of vulvar cancer recurrences with electrochemotherapy – a detailed analysis of possible causes for unsuccessful treatment

Radiology and Oncology, 2023
Electrochemotherapy has good local effectiveness in the treatment of vulvar cancer. Most studies have reported the safety and effectiveness of electrochemotherapy for palliative treatment of gynecological cancers and mostly vulvar squamous cell carcinoma.
Vivod Gregor, Jesenko Tanja, Gasljevic Gorana, Kovacevic Nina, Bosnjak Masa, Sersa Gregor, Merlo Sebastjan, Cemazar Maja   +7 more
doaj   +1 more source