A cautionary tale: Non-steroidal anti-inflammatory drug use and localized provoked vulvodynia. [PDF]
Localized provoked vulvodynia (LPV) is characterized by chronic vulvar pain upon light touch to the vulvar vestibule, a specialized ring of tissue immediately surrounding the vaginal opening. LPV affects ~14 million people in the US.
Chrysilla E +6 more
europepmc +2 more sources
Psychological, Relational, and Fertility-Related Characteristics of Italian Women with Vulvodynia: A Comparative Study with Controls. [PDF]
Vulvodynia, a chronic pain condition affecting the vulvar area, is associated with significant psychological distress and profoundly impacts women’s quality of life.
Gattamelata A +3 more
europepmc +2 more sources
Integrating vaginal laser therapy into multidisciplinary management of bladder pain syndrome and vulvodynia [PDF]
Background Bladder pain syndrome/interstitial cystitis (BPS/IC) and vulvodynia frequently co-occur, forming overlapping pelvic pain syndromes that often evade organ-centered management.
Nobuo Okui
doaj +2 more sources
ObjectiveThe aim of the study was to review the current nomenclature and literature examining microbiome cytokine, genomic, proteomic, and glycomic molecular biomarkers in identifying markers related to the understanding of the pathophysiology and diagnosis of vulvodynia (VVD).Materials and methodsComputerized searches of MEDLINE and PubMed were ...
Havemann, Logan M +7 more
exaly +6 more sources
Help-seeking experiences and intimate partner support in vulvodynia: A qualitative exploration
Background: Vulvodynia is a poorly understood chronic pain condition characterized by persistent and unexplained pain in the vulva. Given the intimate nature of the pain, partners may play an important role in promoting self-management and help-seeking ...
Athina Zoi Lountzi, Hannah Durand
doaj +2 more sources
Vulvodynia is a condition that occurs in 8-10% of women of all ages and is characterized by pain at the vulva that is present during sexual and/or non-sexual situations. Diagnosis is established through careful medical history and pelvic examination, including the cotton-swab test. The onset and maintenance of vulvodynia involves a complex interplay of
Sophie, Bergeron +3 more
+8 more sources
Low-dose naltrexone as a treatment for vulvodynia: A case series
Vulvodynia is a chronic vulvar pain condition that can be challenging to treat and often requires multi-modal interventions for symptom management. Low-dose naltrexone (LDN) is a reversible competitive antagonist at opioid receptors and may have utility ...
Renee T. Sullender +4 more
doaj +2 more sources
Editorial Comment on "Gynecologic Manifestations of Interstitial Cystitis/Bladder Pain Syndrome" by K. E. Whitmore and J. Pires. [PDF]
International Journal of Urology, Volume 33, Issue S1, May 2026.
Wyndaele JJ.
europepmc +2 more sources
Vulvodynia or vulvar pain syndrome is a chronic, heterogeneous, and multifactorial disease with a high prevalence. This condition affects Caucasians, African Americans, Africans and Hispanic women, particularly those sexually active at child-bearing age. The etiology of this condition is complex and remains elusive.
Ventolini, Gary, Barhan, Sheela M.
+11 more sources
Beyond Oral Pain: A Unique Case of Burning Mouth Syndrome With Coexisting Vulvodynia and Cognitive Impairment in a Postmenopausal Woman. [PDF]
ABSTRACT Burning mouth syndrome (BMS) is a chronic pain condition characterized by persistent intraoral burning without an identifiable cause, predominantly affecting postmenopausal women. We present a unique case of a 63‐year‐old Ethiopian woman exhibiting a distinctive triad of BMS, vulvodynia, and progressive cognitive decline, an association not ...
Annam R, De Onaindia M, Partin C.
europepmc +2 more sources

