Results 51 to 60 of about 112,020 (111)

Ospemifene in the Treatment of Vulvovaginal Atrophy

, 2014
Objective: To review the pharmacology, efficacy, and safety of ospemifene in the management of dyspareunia. Data Sources: Literature was sought using PubMed (1966-January 2014) and EMBASE (1973-January 2014).
Forinash, Alicia B., Barnes, Kylie N., Pearce, Erica F., Yancey, Abigail M.   +3 more
core   +1 more source

Genitourinary syndrome of menopause: optimization of therapyfor vaginal symptoms [PDF]

Гинекология, 2018
The aim of the study was to investigate the dynamics of atrophic changes оn the use of low-dose regimens of local therapy with a druge containing only estriol and a druge containing estriol, progesterone and a culture of lactobacilli in patients with ...
E G Eprikyan, S V Yureneva, E I Ermakova, A V Glazunova   +3 more
doaj   +1 more source

Burden of Lower Urinary Tract and Genital Symptoms in Young Transgender Men: Prevalence and Impact on Daily Life

International Journal of Urology, Volume 33, Issue 8, August 2026.
ABSTRACT Objectives To investigate the prevalence of lower urinary tract symptoms (LUTS) and genital symptoms among transgender men in Japan, and to evaluate their impact on daily life, including limitations resulting from concerns about toilet accessibility.
Tomoko Kobayashi, Takatoshi Moriwake, Yusuke Tominaga, Nariaki Ozaki, Satoshi Horii, Ichiro Tsuboi, Kasumi Yoshinaga, Tomoaki Yamanoi, Tatsushi Kawada, Takuya Sadahira, Takehiro Iwata, Satoshi Katayama, Shingo Nishimura, Kensuke Bekku, Yuko Matsumoto, Miyabi Inoue, Masami Watanabe, Ayano Ishii, Toyohiko Watanabe, Motoo Araki   +19 more
wiley   +1 more source

Vulvovaginal atrophy in the peri- and post-menopause: relevance and impact on quality of life [PDF]

, 2022
Vulvovaginal atrophy (VVA) is detected in more than 50% of postmenopausal women, and at 4049 years of age, 15-19% of women have relevant signs. Atrophic changes in the female urogenital system are associated with hypoestrogenism, which results in the ...
Viktor E. Radzinsky, Elizaveta A. Khripach, Mekan R. Orazov, Liudmila M. Mikhaleva, Evgeny D. Dolgov, Elena S. Silantyeva   +5 more
core   +1 more source

The use of topical vaginal estrogens in postpartum women: A systematic review

Acta Obstetricia et Gynecologica Scandinavica, Volume 105, Issue 7, Page 1405-1410, July 2026.
A postpartum reduction in circulating estrogen levels, due to antagonism from elevated prolactin levels, further elevated during breastfeeding, can result in pelvic floor dysfunction, including bladder, bowel and sexual dysfunction, pain and implications for perineal wound healing.
Aysha Waheed, Annika Taithongchai, Dudley Robinson   +2 more
wiley   +1 more source

Differential response of skeletal muscles to mTORC1 signaling during atrophy and hypertrophy [PDF]

, 2013
BACKGROUND: Skeletal muscle mass is determined by the balance between protein synthesis and degradation. Mammalian target of rapamycin complex 1 (mTORC1) is a master regulator of protein translation and has been implicated in the control of muscle mass ...
Handschin, Christoph, Bentzinger, C. Florian, Guridi, Maitea, Castets, Perrine, Hall, Michael N, Tintignac, Lionel A., Hall, Michael N., Perrine Castets, Romanino, Klaas, Tintignac, Lionel, Rüegg, Markus A, Michael N Hall, Lin, Shuo, Markus A Rüegg, Bentzinger, C Florian, Christoph Handschin, Serge Summermatter, Summermatter, Serge, C Bentzinger, Klaas Romanino, Maitea Guridi, Shuo Lin, Rüegg, Markus A., Lionel A Tintignac   +23 more
core   +1 more source

Validation of the DIVAS-Q (Day-to-Day Impact of Vulvovaginal Atrophic Symptoms Questionnaire): a Portuguese patient-reported outcome measure

Journal of Patient-Reported Outcomes
Introduction Portuguese is the fifth most spoken language worldwide. However, no validated patient-reported outcome measure (PROM) is available to assess the impact of vulvovaginal atrophy (VVA) symptoms in Portuguese-speaking women.
Andreia Antunes, Patrício Costa, Ana Alves, Alexandra Colaço, Maria Guarino, Cristina Nogueira-Silva   +5 more
doaj   +1 more source

Modern approach to the management of genitourinary syndrome in women with gynecological malignancies

Radiology and Oncology, 2023
The term genitourinary syndrome of menopause was first used in 2014 by the North American Menopause Society and the International Society for the Study of Women's Sexual Health to describe conditions previously known as atrophic vaginitis, urogenital ...
Kovacevic Nina, Cilensek Ines, Merlo Sebastjan, Segedin Barbara   +3 more
doaj   +1 more source

The Role of Enterococcus faecium in the Synergistic Clearance of High‐Risk HPV: A Clinical Study on Cervicovaginal Microbiota Regulation

Cancer Medicine, Volume 15, Issue 6, June 2026.
ABSTRACT Background Persistent infection with high‐risk human papillomavirus (HR‐HPV) is defined as the principal cause of cervical cancer. Given the important role of cervicovaginal microbiota in HPV acquisition and disease progression, this study aims to evaluate the clinical efficacy of the probiotic Enterococcus faecium (E.
Jun Yang, Mengya Gao, Danfeng Wang, Ziwei Li, Sijing Li, Min Zhou, Li‐Na Hu   +6 more
wiley   +1 more source

Clotrimazole‐loaded PLGA microparticles for local drug delivery to the vagina: Shape does matter

Animal Models and Experimental Medicine, Volume 9, Issue 4, Page 752-764, April 2026.
Clotrimazole‐loaded PLGA microparticles for intravaginal delivery. Abstract Background Intravaginal drug administration is the most promising strategy for treating vaginal infections to protect women's health, such as vulvovaginal candidiasis (VVC). However, conventional vaginal formulations in the clinic face challenges such as drug leakage and low ...
Yanyu Li, Jingting Luo, Shitao Zou, Xin Zhang, Zhen Wang, Ziwen Jiang, Jingjie Wang, Zhaoxia Liu, Zhimin Zhou   +8 more
wiley   +1 more source