An Active Role for the Ribosome in Determining the Fate of Oxidized mRNA
Chemical damage to RNA affects its functional properties and thus may pose a significant hurdle to the translational apparatus; however, the effects of damaged mRNA on the speed and accuracy of the decoding process and their interplay with quality ...
Carrie L. Simms +4 more
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Researchers May Need Additional Data Curation Support
A Review of: Johnston, L. R., Carlson, J., Hudson-Vitale, C., Imker, H., Kozlowski, W., Olendorf, R., & Stewart, C. (2018). How important are data curation activities to researchers? Gaps and opportunities for academic libraries.
Robin E. Miller
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AT a meeting of friends and admirers of W. H. Hudson, held at Messrs. Dent's on November 28, it was agreed that a fitting memorial in stone should be placed in or near one of the sanctuaries in the London parks which should be dedicated to his memory, subject to the consent of H.M. Office of Works.
openaire +2 more sources
Outcomes in Patients with Suprachoroidal Hemorrhage After Anterior Segment Surgery
Jason Fan, Julia L Hudson, Parastou Pakravan, Thomas A Lazzarini, Benjamin R Lin, Kenneth C Fan, Nicolas A Yannuzzi, Jayanth Sridhar, Justin H Townsend, Audina M Berrocal, William E Smiddy, Elizabeth A Vanner, Harry W Flynn Jr Department of Ophthalmology,
Fan J +12 more
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Contribution of the two genes encoding histone variant h3.3 to viability and fertility in mice. [PDF]
Histones package DNA and regulate epigenetic states. For the latter, probably the most important histone is H3. Mammals have three near-identical H3 isoforms: canonical H3.1 and H3.2, and the replication-independent variant H3.3.
Michelle C W Tang +11 more
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Uncovering an allosteric mode of action for a selective inhibitor of human Bloom syndrome protein
BLM (Bloom syndrome protein) is a RECQ-family helicase involved in the dissolution of complex DNA structures and repair intermediates. Synthetic lethality analysis implicates BLM as a promising target in a range of cancers with defects in the DNA damage ...
Xiangrong Chen +13 more
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R. B. Cunninghame Graham’s “Aurora La Cujiñi” (1898) : An Exploration / Aurora La Cujiñi” (1898) de R. B. Cunninghame Graham - Una indagación [PDF]
: In Aurora La Cujiñi-A realistic sketch in Seville, published by the Scottish writer R. B. Cunninghame Graham in 1898, the frontispiece showed the sepia image of a female flamenco dancer. What might ‘La Cujiñi’ mean?
John C. Mc Intyre
doaj
Surface single-molecule dynamics controlled by entropy at low temperatures
STM is capable of imaging the configurations of molecules on surfaces and measuring the rate of transitions between them. Here the authors demonstrate that, controlled by the STM tip position, the entropic and conservative forces on the molecule can ...
J. C. Gehrig +6 more
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Skeletal muscle mitochondrial volume and myozenin-1 protein differences exist between high versus low anabolic responders to resistance training [PDF]
Background We sought to examine how 12 weeks of resistance exercise training (RET) affected skeletal muscle myofibrillar and sarcoplasmic protein levels along with markers of mitochondrial physiology in high versus low anabolic responders.
Michael D. Roberts +12 more
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Nitric oxide-releasing gel accelerates healing in a diabetic murine splinted excisional wound model
IntroductionAccording to the American Diabetes Association (ADA), 9–12 million patients suffer from chronic ulceration each year, costing the healthcare system over USD $25 billion annually.
Dharshan Sivaraj +25 more
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