Results 71 to 80 of about 459,435 (338)
Pre‐Encoded IFN‐I Sensitivity Exacerbates Memory T Cell Senescence in Solid Tumors
Advanced Science, EarlyView.Type I interferon (IFN‐I) signaling promotes p21‐dependent cell cycle arrest in senescent tumor‐specific memory T cells, resulting in poor proliferative responses and solid tumor regression during cancer vaccination. Conversely, IFNα/β receptor blockade reinvigorates T cell proliferation to regress solid tumors and is more effective with increasing ...
Andrew Nguyen +4 more
wiley +1 more source
The demand for private health insurance: do waiting lists or waiting times matter? CHERE Working Paper 2010/8 [PDF]
Besley, Hall, and Preston (1999) estimated a model of the demand for private health insurance in Britain as a function of regional waiting lists and found that increases in the number of people waiting for more than 12 months (the long-term waiting list)
Elizabeth Savage +4 more
core
Waiting for Their Chance: A Closer Look at Wait Lists in Urban Public Charter Schools [PDF]
, 2015 Public charter schools are finally giving parents an alternative to the low-performing school systems in the nation's biggest cities. Unfortunately, in communities with few high-quality public school options, the demand for charter schools is ...
Nora Kern, Susan Pendergrass
core
Targeting the PDK1/c‐Myc/SOX10 Signaling in Oligodendrocytes Alleviates Neuropathic Pain
Advanced Science, EarlyView.This work reveals that oligodendrocyte homeostasis, mediated by PDK1, is a critical determinant of neuropathic pain (NPP) pathogenesis. Disruption of PDK1 in oligodendrocytes impairs SOX10‐dependent myelination programs through c‐Myc accumulation, leading to disrupted myelination and the pathophysiology of NPP.
Pingping Qiao +7 more
wiley +1 more source
Implementing Centralized Waiting Lists for Patients without a Family Physician in Québec
Health Reform Observer - Observatoire des Réformes de Santé, 2014 In 2008, the Québec government mandated the ninety-four Centres de Santé et des Services Sociaux (CSSS or Centres for Health and Social Services) to implement a Guichet d’Accès aux Clientèles Orphelines (GACO)—a centralized waiting list to help patients
Mylaine Breton +2 more
doaj
Waiting Times and Cost Sharing for a Public Health Care Service with a Private Alternative: A Multi-agent Approach [PDF]
Cost sharing represent a well-established tool for the control of health care demand in many Oecd countries, even though it is used with caution, and in combination with other instruments, in order to avoid potential negative impacts on access to ...
Dino Rizzi, Vincenzo Rebba
core
Improving Awareness of Transportation Services in Lamoille County [PDF]
, 2019 This project was aimed to identify and address transportation needs of patients in Lamoille County to their medical appointments. A handout was created, which lists all of the transportation resources in the county that are available to patients.
Searles, Sienna
core +1 more source
Mechanism for Powerlaws without Self-Organization
, 2001 A recent claim has been made in the journal Nature that there must be a self-regulation in the waiting times to see hospital consultants on the ground that the relative changes in the size of waiting lists follow a power law.
Sornette, D.
core +2 more sources
Reviewing the review process : examining decision-making in practice [PDF]
, 2001 A national multi-disciplinary audit showed variation in SLT practice on the decision to review pre-school children or place them on waiting lists following initial assessment.
Anderson, Carolyn, van der Gaag, Anna
core +1 more source
Advanced Science, EarlyView.This study developed a hierarchical targeting nanoplatform, siTREM2@ETP‐PEOz‐OMVs, against triple‐negative breast cancer (TNBC) bone metastasis. It precisely delivers therapeutic siTREM2 to monocytes/macrophages within the metastatic niche. This intervention dually regulates cell fate: reprogramming immunosuppressive macrophages and inhibiting ...
Fanglu Chen +12 more
wiley +1 more source