Results 111 to 120 of about 9,782,671 (248)
Structural Polymorphism of polyG Inclusions Revealed by In Situ Cryo‐Electron Tomography
Advanced Science, EarlyView.Correlative cryo‐electron tomography in primary cortical neurons and NIID mouse brain tissue reveals that polyG inclusions are interconnected ribbon‐like assemblies rather than canonical amyloid fibrils. Multiple compartment‐specific ribbon states show distinct 26S proteasome accessibility, while cytoplasmic ribbons contact and deform ER‐like ...
Yunwen Qian +12 more
wiley +1 more source
Advanced Science, EarlyView.Polydopamine nanoparticles enable a precise, non‐genetic, and transcranial neuromodulation strategy via near‐infrared photothermal stimulation. By activating TRPV1 channels, this approach specifically enhances hippocampal gamma oscillations, thereby rescuing spatial memory deficits in models of perioperative neurocognitive disorder.
Yan‐Bo Zhou +10 more
wiley +1 more source
Wake Forest Magazine [Spring 2025]
This is the issue of the Spring 2025 Wake Forest Magazine. It primarily explores mentorship across generations within the Wake Forest University community. Through essays, interviews, and feature stories, the magazine highlights how relationships between
core +1 more source
Advanced Science, EarlyView.Different kirigami patterns are proposed and the parameters are optimized by comparing the out‐of‐plane deformation behavior. Then, the proposed patterns are fabricated on PVDF film using laser technology. The deformed kirigami‐cut PVDF is embedded into PDMS to construct pressure senor.
Xiaodong Huang +6 more
wiley +1 more source
Church Minutes, Vol. 1, 1835-1876 (Wake Forest Baptist Church, Wake Forest, NC)
, 2022 Minutes of Wake Forest Baptist Church (Wake Forest, NC) conferences from the organization of the church, Aug.
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Advanced Science, EarlyView.A non‐filamentary self‐rectifying HfO2/TiOx resistive random‐access memory integrates H2 annealing with an incremental step pulse with verify algorithm to achieve stable and linear analog conductance modulation. The device enables low‐current 6‐bit multilevel operation while suppressing sneak current in crossbar arrays. Implemented in Transformer‐based
Seonjeong Lee +5 more
wiley +1 more source
Wake Forest Magazine [Summer 2024]
The Summer 2024 issue of Wake Forest Magazine is a special edition dedicated to the life and legacy of Provost Emeritus Edwin Graves Wilson (1923-2024). Known affectionately as "Mr.
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Therapeutic Gene Editing of APOE4 in Sporadic Alzheimer's Disease via Prime Editor 7
Advanced Science, EarlyView.Prime Editor 7‐mediated conversion of APOE4 to APOE3 alleviates Alzheimer's disease‐associated pathology in AD mouse models and patient‐derived neurons and improves cognitive performance in vivo, supporting therapeutic genome editing as a promising strategy for APOE4‐associated neurodegeneration.
Yunkyung Kim +16 more
wiley +1 more source
Advanced Science, EarlyView.An antiferroelectric tunnel junction serves as a reservoir computing node, where field‐induced phase transitions and spontaneous ZrO2 relaxation deliver nonlinear fading memory. An In‐Ga‐Zn oxide interlayer enlarges the memory margin and multibit state richness.
Taegyu Kwon +13 more
wiley +1 more source