Results 41 to 50 of about 132,762 (268)

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina, Anna Marcé‐Grau, Barbara Masotto, Marta Codina, Lamia BenJemaa, Yasmina Elaribi, Mónica Martinez‐Gallo, Roger Colobran, Angel Sanchez‐Montañez, Irene Valenzuela, Yoshiko Murakami, Alfons Macaya   +11 more
wiley   +1 more source

Efficacy of Intermittent Theta‐Burst Stimulation for Prolonged Disorders of Consciousness: A Prospective, Randomized, Controlled Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Emerging evidence suggests that low‐frequency neural oscillations are dynamically regulated by consciousness levels, with the recovery of low cortical activity potentially serving as a neurophysiological substrate for conscious emergence. Targeted enhancement of these low‐frequency rhythms in patients with disorders of consciousness
Chuan Xu, Jun Hu, Qianqian Wu, Min Wu, Yamei Yu, Hangcheng Li, Jian Gao, Jingqi Li, Nai Ding, Jie Yu, Benyan Luo   +10 more
wiley   +1 more source

A Calibration Procedure for an Analytical Wake Model Using Wind Farm Operational Data

Energies, 2020
Wind energy is one of the fastest growing renewable energy sources in the U.S. Wind turbine wakes change the flow field within wind farms and reduce power generation. Prior research has used experimental and computational methods to investigate and model
Jian Teng, Corey D. Markfort
doaj   +1 more source

Optimal combined wake and active power control of large‐scale wind farm considering available power

IET Renewable Power Generation, 2023
The high‐order nonlinear complex characteristics of traditional static wake model (SWM) restrict the fast optimization of wake effect. Therefore, this paper introduces a dynamic wake model (DWM) to describe the time‐varying wake characteristics of wind ...
Weimin Chen, Pengda Wang, Sheng Huang, Lingxiang Huang, Wenbo Tang, Qiuwei Wu   +5 more
doaj   +1 more source

Characteristics of the meandering effect in a stratified wake

Physical Review Fluids
The gradual suppression of the vertical motions and the emergence of large-scale horizontal structures are characteristics of a stratified wake flow. We isolate the resulting wake meandering from the stationary velocity, i.e., the velocity without meandering, by utilizing direct numerical simulations covering Reynolds numbers $Re_B=UD/ν$ between $[10 ...
Xinyi Huang, Jiaqi J. L. Li
openaire   +2 more sources

Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz, Christopher H. Thompson, Linda C. Laux, Alfred L. George Jr.   +3 more
wiley   +1 more source

Added Prognostic Value of EEG Reactivity in Comatose Patients Following Cardiac Arrest

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives To evaluate the added prognostic value of EEG reactivity for favorable outcome compared with background analysis during and after targeted temperature management (TTM). Methods Prospective observational cohort study of comatose post–cardiac arrest patients admitted to a single academic center between 2017 and 2022, all undergoing ...
Sarah Caroyer, Marie Obrecht, Charlotte de Maeseneire, Charlotte Damien, Chantal Depondt, Lorenzo Ferlini, Estelle Rikir, Filippo Annoni, Fabio Silvio Taccone, Nicolas Mavroudakis, Benjamin Legros, Nicolas Gaspard   +11 more
wiley   +1 more source

On Blockage Effects for a Tidal Turbine in Free Surface Proximity

Energies, 2019
Experiments with a three-bladed, constant chord tidal turbine were undertaken to understand the influence of free surface proximity on blockage effects and near-wake flow field.
Nitin Kolekar, Ashwin Vinod, Arindam Banerjee   +2 more
doaj   +1 more source

Dynamic Stall Model for Tower Shadow Effects on Downwind Turbines and Its Scale Effects

Energies, 2020
A dynamic stall model for tower shadow effects is developed for downwind turbines. Although Munduate’s model shows good agreement with a 1.0 m wind tunnel test model, two problems exist: (1) it does not express load increase before the entrance of the ...
Shigeo Yoshida
doaj   +1 more source

White Matter Hyperintensity Burden and Short‐Interval Change Associated With Sleep Apnoea in the UK Biobank

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Purpose White matter hyperintensities (WMH) are a core neuroimaging marker of cerebral small vessel disease (CSVD). Sleep apnoea (SA) is a recognized vascular risk factor, but its associations with regional WMH burden, short‐interval WMH change and cognitive performance in population‐based cohorts remain incompletely defined. We
Peng Cheng, Diego Z. Carvalho, Shahid Karim, Anwar Chahal, Virend K. Somers   +4 more
wiley   +1 more source