Results 261 to 270 of about 142,074 (316)

Endothermy, neuron counts, and other issues: Further remarks on neurocognitive evolution in fossil vertebrates

The Anatomical Record, EarlyView.
Abstract Last year, we challenged the view that large‐bodied theropod dinosaurs such as Tyrannosaurus rex resembled primates in cognition and behavior, a proposition made by Herculano‐Houzel in 2023. More recently, Jensen et al. have criticized our work on this topic, raising methodological and conceptual issues.
Kai R. Caspar, Cristián Gutiérrez‐Ibáñez, Hady George, Thomas R. Holtz Jr., Darren Naish, Grant R. Hurlburt   +5 more
wiley   +1 more source

High-resolution sleep fragmentation assessment in narcolepsy type 1 and their non-narcoleptic siblings: a 5-s mini-epoch study. [PDF]

Sleep
Follin LF, Viste R, Vevelstad J, Langdalen K, Hansen BH, Grande RKB, Kaufmann T, Christensen JAE, Zahid AN, Viken MK, Juvodden HT, Knudsen-Heier S.   +11 more
europepmc   +1 more source

Inosine‐Triphosphate‐Pyrophosphatase Activity as a Potential Predictor of Methotrexate Remission in Juvenile Idiopathic Arthritis

Arthritis &Rheumatology, EarlyView.
Objective Methotrexate (MTX) is the first‐line therapy for juvenile idiopathic arthritis (JIA), but up to 40% of patients do not respond to it. Low inosine triphosphate pyrophosphatase (ITPA) activity has been associated with reduced clinical remission. We investigated the role and underlying mechanisms of ITPA in vitro. Methods ITPA enzymatic activity
Sofia Sindici Forgiarini, Marianna Lucafò, Debora Curci, Davide Selvestrel, Valentina Moressa, Sofia Pagarin, Barbara Bellich, Martina Franzin, Alberto Tommasini, Mara L. Becker, Laura B. Ramsey, Susan D. Thompson, Carl D. Langefeld, Federica Corba, Edoardo Marrani, Gabriele Simonini, Gabriele Stocco, Giuliana Decorti, Andrea Taddio, Serena Pastore   +19 more
wiley   +1 more source

Negative allosteric modulator of the metabotropic glutamate receptor 7 ADX71743 increases wakefulness, reduces sleep, and alters stress-induced changes in the brain neurotransmitter levels. [PDF]

Int J Neuropsychopharmacol
Kalinichev M, Gruner JA, Flik G, Heins M, Haddouk H, Royer-Urios I, Bate ST, Poli S, Lütjens R.   +8 more
europepmc   +1 more source

Clock Genes Regulate Ca2+ Signaling and Mitochondrial Bioenergetics to Inhibit Sjögren Disease

Arthritis &Rheumatology, EarlyView.
Objective Although Ca2+ signaling and metabolism have been identified as key determinants for the development of Sjögren disease (SjD), the intricate connection between them and salivary gland physiology remains poorly understood. Methods Fluorescence‐based Ca2+ imaging, RNA sequencing, and mitochondrial activity were used to investigate the effects of
Viktor R. Drel, Manigandan Venkatesan, Rahul S. Jasrotia, Yuyang Sun, Viviane Nascimento da Conceicao, Neelanjan Vishnu, Shankara N. Varadarajan, Venugopal R. Bovilla, Rajender K. Motiani, Shobhan Gaddameedhi, Bibhuti B. Mishra, Muniswamy Madesh, Brij B. Singh   +12 more
wiley   +1 more source

AI-Driven Sleep Staging Using Instantaneous Heart Rate and Accelerometry: Insights From an Apple Watch Study. [PDF]

IEEE Trans Biomed Eng
Song TA, Zhang Y, Zhou Z, Hou L, Malekzadeh M, Behzad A, Dutta J.   +6 more
europepmc   +1 more source

Beyond the grave: Do the dead have rights?

Anatomical Sciences Education, EarlyView.
Abstract Anatomists who work with the Dead often see themselves as custodians of the Dead. To those who opine that the Dead no longer have Rights (legal or moral) or privileges and have nothing more to contribute to the development of Society or to human endeavor, the Dead's custodians might respond that there is ample evidence that some Rights and ...
Beverley Kramer, Bernard Moxham
wiley   +1 more source

Field assessment of melatonin timing reveals circadian misalignment beyond chronotype in elite female football players. [PDF]

NPJ Biol Timing Sleep
Reis C, Tomás R, Cardoso V, Costa JA, Brito J.   +4 more
europepmc   +1 more source

Charlotte Pommer: Resistance fighter and female pioneer of German anatomy

Anatomical Sciences Education, EarlyView.
Abstract This article examines the biography and unique case of Charlotte Pommer (1914–2004), the only anatomist documented to have left the field during the Nazi period after encountering the regime's victims on the dissection table. While she is known for her resistance activities, newly presented documentation reveals her role as the provisional ...
Tim S. Goldmann
wiley   +1 more source