Results 111 to 120 of about 98,388 (350)

Sleep magnetoencephalography enhances detection and source imaging of seizures and fast oscillations in focal cortical dysplasia

Epilepsia, EarlyView.
Abstract Objective Focal cortical dysplasia (FCD) causes drug‐resistant epilepsy requiring presurgical evaluation. Invasive electroencephalographic (EEG) studies demonstrate that sleep modulates epileptic activity, including interictal epileptiform discharges (IEDs), fast oscillations (FOs) in the beta (14–40 Hz) and gamma (40–80 Hz) frequency bands ...
Marcel Heers, Jawata Afnan, Christoph Braun, Christophe Grova, Dirk‐Matthias Altenmüller, Bernhard J. Steinhoff, Matthias Dümpelmann, Theo Demerath, Horst Urbach, Silke Ethofer, Markus Siegel, Andreas Schulze‐Bonhage, Holger Lerche, Yiwen Li Hegner   +13 more
wiley   +1 more source

Corrigendum: Estimating the Minimal Number of Repeated Examinations for Random Responsiveness With the Coma Recovery Scale—Revised as an Example

Frontiers in Integrative Neuroscience, 2021
Hao Yang, Chengyin Ye, Xiaochen Liu, Lingxiu Sun, Anqi Wang, Jing Wang, Nantu Hu, Xiaohua Hu, Olivia Gosseries, Steven Laureys, Haibo Di, Jiqian Fang   +11 more
doaj   +1 more source

Sleep, recovery, and metaregulation: explaining the benefits of sleep

Nature and Science of Sleep, 2015
Vladyslav V VyazovskiyDepartment of Physiology, Anatomy, and Genetics, University of Oxford, Oxford, UKAbstract: A commonly held view is that extended wakefulness is causal for a broad spectrum of deleterious effects at molecular, cellular, network ...
Vyazovskiy VV
doaj  

Enhancing sleep, wakefulness, and cognition with transcranial photobiomodulation: a systematic review

Frontiers in Behavioral Neuroscience
Disruptions in sleep are common across clinical populations, particularly those with neurological and psychiatric disorders, making restorative sleep and sustained wakefulness a public health priority.
Naomi L. Gaggi, Zamfira Parincu, Anna Peterson, Courtney O’Brien, Korey Kam, Umit Tural, Indu Ayappa, Andrew W. Varga, Dan V. Iosifescu, Dan V. Iosifescu, Ricardo S. Osorio, Ricardo S. Osorio   +11 more
doaj   +1 more source

Roles of Microglial Phagocytosis and Inflammatory Mediators in the Pathophysiology of Sleep Disorders

Frontiers in Cellular Neuroscience, 2017
Sleep serves crucial learning and memory functions in both nervous and immune systems. Microglia are brain immune cells that actively maintain health through their crucial physiological roles exerted across the lifespan, including phagocytosis of ...
Agnes Nadjar, Agnes Nadjar, Agnes Nadjar, Henna-Kaisa M. Wigren, Marie-Eve Tremblay, Marie-Eve Tremblay   +5 more
doaj   +1 more source

Sleep dysfunction and EEG alterations in mice overexpressing alpha-synuclein. [PDF]

, 2014
BackgroundSleep disruptions occur early and frequently in Parkinson's disease (PD). PD patients also show a slowing of resting state activity. Alpha-synuclein is causally linked to PD and accumulates in sleep-related brain regions.
Chesselet, Marie-Françoise, McDowell, Kimberly A, Roos, Kenneth P, Shin, David   +3 more
core  

Tissue oxygenation dynamics during transition from seizure to spreading depolarization in rat brain

Epilepsia, EarlyView.
Abstract Objective Spreading depolarization (SD) is a phenomenon underlying various neurological conditions, including epilepsy. Researchers have suspected that local tissue oxygenation breakdown induces spontaneous SD. In this study, we investigated the relationship between spontaneous epileptic seizures and SD, with a focus on the role of local ...
Jiayang Liu, Bruce J. Gluckman
wiley   +1 more source

Sleep and Neurochemical Modulation by DZNep and GSK-J1: Potential Link With Histone Methylation Status

Frontiers in Neuroscience, 2019
Histone methylation/demethylation plays an important modulatory role in chromatin restructuring, RNA transcription and is essential for controlling a plethora of biological processes.
Eric Murillo-Rodríguez, Eric Murillo-Rodríguez, Gloria Arankowsky-Sandoval, Jorge Aparecido Barros, Jorge Aparecido Barros, Nuno Barbosa Rocha, Nuno Barbosa Rocha, Tetsuya Yamamoto, Tetsuya Yamamoto, Sérgio Machado, Sérgio Machado, Henning Budde, Henning Budde, Henning Budde, Diogo Telles-Correia, Diogo Telles-Correia, Diogo Monteiro, Diogo Monteiro, Diogo Monteiro, Luis Cid, Luis Cid, Luis Cid, André Barciela Veras, André Barciela Veras   +23 more
doaj   +1 more source

CaMKIIβ insufficiency disrupts cortical networks, producing aberrant low‐gamma oscillations and seizure susceptibility

Epilepsia, EarlyView.
Abstract Objective Pathogenic variants in the calcium/calmodulin‐dependent protein kinase II B gene (CAMK2B) have been associated with neurodevelopmental disorders, including epilepsy, yet the mechanisms underlying cortical dysfunction remain largely unclear.
Hiroki Mutoh, Kazushi Aoto, Atsuo Fukuda, Hirotomo Saitsu   +3 more
wiley   +1 more source

Compound heterozygous SLC12A5 variants expand the molecular and functional spectrum of KCC2‐developmental and epileptic encephalopathy

Epilepsia, EarlyView.
Overview of the multimodal experimental approach integrating clinical, genetic, in silico, and in vitro investigations. Clinical: Representative EEG recording setup and ictal traces from affected patients. Genetic: Pedigrees for Families A and B highlighting the inheritance of the four identified SLC12A5 variants (A1, A2, B1, B2).
Mira Hamze, Robyn Whitney, Dorothée Ville, Nathalie Villeneuve, Anna‐Maria Hartmann, Lisa Becker, Jens Hausmann, Jinwei Zhang, Cathy Brier, Lucie I. Pisella, Perrine Friedel, Audrey Labalme, Eudeline Alix, Nicolas Chatron, Damien Sanlaville, Sylvie Gory‐Fauré, Eric Denarier, Christophe Porcher, Gaetan Lesca, Igor Medina   +19 more
wiley   +1 more source