Brainwide hemodynamics predict EEG neural rhythms across sleep and wakefulness in humans
Leandro P. L. Jacob +4 more
openalex +1 more source
Characterisation of sleep apneas and respiratory circuitry in mice lacking CDKL5
Summary CDKL5 deficiency disorder is a rare genetic disease caused by mutations in the CDKL5 gene. Central apneas during wakefulness have been reported in patients with CDKL5 deficiency disorder. Studies on CDKL5‐knockout mice, a CDKL5 deficiency disorder model, reported sleep apneas, but it is still unclear whether these events are central (central ...
Gabriele Matteoli +12 more
wiley +1 more source
Differential engagement of thalamic nuclei orchestrates consciousness states across anesthesia, sleep, and disorders of consciousness. [PDF]
Lu F +8 more
europepmc +1 more source
Sex‐based disparities in dopamine agonist response in patients with restless legs syndrome
Summary This study aimed to investigate sex‐related differences in the response to ropinirole and pramipexole in patients with restless legs syndrome (RLS). By analysing clinical parameters and polysomnographic (PSG) findings, we sought to elucidate the potential factors related to sex disparities modulating treatment responses and sleep quality in RLS.
Maria P. Mogavero +9 more
wiley +1 more source
The Ontogenetic Development of Rapid Eye Movement Sleep in Early Life and Its Regulatory Mechanisms. [PDF]
Zhang XJ +8 more
europepmc +1 more source
Summary Boosting slow‐wave activity (SWA) by modulating slow waves through closed‐loop auditory stimulation (CLAS) might provide a powerful non‐pharmacological tool to investigate the link between sleep and neurodegeneration. Here, we established mouse CLAS (mCLAS)‐mediated SWA enhancement and explored its effects on sleep deficits in neurodegeneration,
Inês Dias +5 more
wiley +1 more source
Profiling the sleep architecture of ageing adults using a seven‐state continuous‐time Markov model
Summary Sleep is a complex biological process regulated by networks of neurons and environmental factors. As one falls asleep, neurotransmitters from sleep–wake regulating neurones work in synergy to control the switching of different sleep states throughout the night. As sleep disorders or underlying neuropathology can manifest as irregular switching,
Jonathon Jacobs +3 more
wiley +1 more source
Sleep staging through an unsupervised learning lens. [PDF]
Christopoulos A, Tzovara A.
europepmc +1 more source
Decrease of excessive daytime sleepiness after shunt treatment for normal pressure hydrocephalus
Summary Sleepiness and apathy are often reported in patients with normal pressure hydrocephalus. However, research on outcomes after shunt surgery has mainly focused on the classical triad symptoms, that is, gait, cognition, and bladder dysfunction. This study aimed to describe the effects of shunt treatment on excessive daytime sleepiness and whether ...
Simon Lidén +4 more
wiley +1 more source

