Results 181 to 190 of about 55,000 (288)

A new perspective on drug‐resistant epilepsy in children with focal cortical dysplasia type 1: From challenge to favorable outcome

Epilepsia, Volume 66, Issue 3, Page 632-647, March 2025.
Abstract Objective We comprehensively characterized a large pediatric cohort with focal cortical dysplasia (FCD) type 1 to expand the phenotypic spectrum and to identify predictors of postsurgical outcomes. Methods We included pediatric patients with histopathological diagnosis of isolated FCD type 1 and at least 1 year of postsurgical follow‐up.
Barbora Splitkova, Katerina Mackova, Miroslav Koblizek, Zuzana Holubova, Martin Kyncl, Katerina Bukacova, Alice Maulisova, Barbora Straka, Martin Kudr, Matyas Ebel, Alena Jahodova, Anezka Belohlavkova, Gonzalo Alonso Ramos Rivera, Martin Hermanovsky, Petr Liby, Michal Tichy, Josef Zamecnik, Radek Janca, Pavel Krsek   +18 more
wiley   +1 more source

Neuronal oscillatory imbalances in GNAO1‐related disorders associated with disease severity

Epilepsia, EarlyView.
Abstract Objective This study investigates excitatory/inhibitory (E/I) imbalances in GNAO1‐related disorders (GNAO1‐RD), linking neuronal dysfunction to clinical severity using E/I‐sensitive electroencephalography (EEG) analyses. Methods We conducted an observational study involving 12 children with GNAO1‐RD caused by pathogenic variants and 36 age ...
Tongyu Wang, Jana Domínguez‐Carral, William Grant Ludlam, Mar Junyent Segarra, Montserrat Fornaguera Marti, Hilgo Bruining, Kirill A. Martemyanov, Klaus Linkenkaer‐Hansen, Juan Dario Ortigoza‐Escobar   +8 more
wiley   +1 more source

Resting-state fMRI in sleeping infants more closely resembles adult sleep than adult wakefulness [PDF]

, 2017
Botteron, Kelly N, et al.,, Mitra, Anish, Pruett, John R, Jr., Raichle, Marcus, Schlaggar, Bradley L, Snyder, Abraham Z   +6 more
core   +1 more source

Changes in Body Temperature and Sleep‐Wakefulness AfterIntrapreoptic Injection of Methoxamine in Rats [PDF]

, 2003
Ra. Vetrivelan, Hruda Nanda Mallick, Velayudhan Mohan Kumar   +2 more
openalex   +1 more source

Distinct spike‐and‐wave EEG profiles reveal susceptibility to fleeting/almost loss of consciousness (so‐called blips) in generalized epilepsy

Epilepsia, EarlyView.
Abstract Objective To characterize electroencephalographic (EEG) profiles of short spike‐and‐wave bursts (SWBs) in patients with idiopathic generalized epilepsy reporting sensations of fleeting/almost loss of consciousness, described as “a blip on the screen”—a phenomenon first termed “blips” by J.W. Lance.
Edgar Matringe, Aya Khalaf, Romain Granchamp, Juan R. Vidal, Marcela Perrone‐Bertolotti, Hal Blumenfeld, Laurent Vercueil   +6 more
wiley   +1 more source

Interactions between GABAergic and Cholinergic Processes in the Nucleus Pontis Oralis: Neuronal Mechanisms Controlling Active (Rapid Eye Movement) Sleep and Wakefulness [PDF]

, 2004
Ming-Chu Xi, Francisco R. Morales, Michael H. Chase   +2 more
openalex   +1 more source

Familial adult myoclonus epilepsy: A comprehensive diagnostic strategy for clinical practice

Epilepsia, EarlyView.
Abstract Familial adult myoclonus epilepsy (FAME) is a genetic neurological disorder characterized by cortical myoclonus and epileptic seizures with clinical features that overlap with other movement disorders and epileptic syndromes, particularly essential tremor (ET), progressive myoclonic epilepsy (PME), and juvenile myoclonic epilepsy (JME).
Yitao Lu, Yi Ge, Ruyi Wang, Yang Zheng, Jiping Zhou, Zhongjin Wang, Chunhong Shen, Shan Wang, Lingli Hu, Bo Wang, Zhidong Cen, Wei Luo, Meiping Ding, Shuang Wang, Yao Ding   +14 more
wiley   +1 more source

What Keeps Us Awake: the Neuropharmacology of Stimulants and Wakefulness Promoting Medications [PDF]

, 2004
Benjamin Boutrel, George F. Koob
openalex   +1 more source

Long‐read sequencing of recurrent FGF12 duplications in epilepsy: Insights into structural mechanisms and aberrant isoforms

Epilepsia, EarlyView.
Abstract Objective Fibroblast growth factor 12 (FGF12), a member of the fibroblast homologous factor family, plays a key role in the modulation of voltage‐gated sodium (Nav) channels. Pathogenic variants in the FGF12 gene leading to a gain‐of‐function mechanism and partial duplication encompassing the FGF12 gene leading to a loss‐of‐function mechanism ...
Jade Fauqueux, Laurence Chaton, Pierre Cleuziou, Anne‐Sophie Diependaële, Nathalie Bach, Nicolas Gruchy, Marion Gerard, Jean‐Pascal Meneboo, Céline Villenet, Martin Figeac, Emilie Ait‐Yahya, Caroline Thuillier, Elise Boudry, Adeline Trauffler, Sylvie Nguyen‐The‐Tich, Simon Boussion, Roseline Caumes, Jamal Ghoumid, Thomas Smol   +18 more
wiley   +1 more source

1140 Loratidine use leads to increased wakefulness and motivation when compared to cetrizine in patients with allergic rhinitis

, 2000
D. Gates
openalex   +1 more source