Role of Preoptic Area γ-Aminobutyric Acid-mediated Neurons in Distinctly Regulating Sleep and Rousability during Dexmedetomidine Sedation in Mice. [PDF]
Qiu G +15 more
europepmc +1 more source
Structural insights into the binding mode of the hypnotic drug vornorexant to orexin receptors
The crystal structure of the human orexin type 2 receptor–vornorexant complex (3.29 Å resolution) and orexin type 1 receptor docking revealed a conserved U‐shaped binding conformation, explaining the high affinity and balanced dual antagonism of this dual orexin receptor antagonist. The structural data validate the rational design that incorporated a 1,
Masashi Mima +4 more
wiley +1 more source
Highly mechanically stable PEDOT:PSS/PDA-modified microelectrode arrays reveal state-specific dynamic neural activity across sleep-wake. [PDF]
Miao J +11 more
europepmc +1 more source
The association between sleep disturbance and stimulant use: A cross‐lagged examination
Abstract Background and aims Sleep disruptions increase the risk of substance misuse. Substance use—especially stimulants—can increase acute and chronic sleep dysfunction. This study aimed to estimate the associations between sleep disturbance and stimulant use over time among participants with stimulant use disorder (StUD).
Viviana E. Horigian +12 more
wiley +1 more source
An updated systematic review and meta-analysis of modafinil for excessive daytime sleepiness in narcolepsy. [PDF]
Mann GS +5 more
europepmc +1 more source
Barren environments increase 'wakeful' inactivity in veal calves
Webb, L.E. +3 more
openalex +1 more source
Stress ensemble in the BNST mediates comorbid anxiety and sleep disruption. [PDF]
Sun H +11 more
europepmc +1 more source
Unusual Theta Brain Waves During Full Wakefulness: Study of a Remarkable Mind
Brain Science Researcher
openalex +1 more source

