Ageing‐related modification of sleep and breathing in orexin‐knockout narcoleptic mice
Summary Narcolepsy type‐1 (NT1) is a lifelong sleep disease, characterised by impairment of the orexinergic system, with a typical onset during adolescence and young adulthood. Since the wake–sleep cycle physiologically changes with ageing, this study aims to compare sleep patterns between orexin‐knockout (KO) and wild type (WT) control mice at ...
Stefano Bastianini+7 more
wiley +1 more source
Influence of lighting on sleep behaviour, circadian rhythm and spontaneous blink rate in stabled riding school horses (Equus caballus). [PDF]
Greening L+8 more
europepmc +1 more source
Characterisation of sleep apneas and respiratory circuitry in mice lacking CDKL5
Summary CDKL5 deficiency disorder is a rare genetic disease caused by mutations in the CDKL5 gene. Central apneas during wakefulness have been reported in patients with CDKL5 deficiency disorder. Studies on CDKL5‐knockout mice, a CDKL5 deficiency disorder model, reported sleep apneas, but it is still unclear whether these events are central (central ...
Gabriele Matteoli+12 more
wiley +1 more source
Neuropathic pain impairs sleep architecture, non-rapid eye movement sleep, and reticular thalamic neuronal activity. [PDF]
López-Canul M+6 more
europepmc +1 more source
Normal Sleep and Circadian Rhythms: Neurobiologic Mechanisms Underlying Sleep and Wakefulness
Dimitri Markov, Marina Goldman
openalex +2 more sources
Sex‐based disparities in dopamine agonist response in patients with restless legs syndrome
Summary This study aimed to investigate sex‐related differences in the response to ropinirole and pramipexole in patients with restless legs syndrome (RLS). By analysing clinical parameters and polysomnographic (PSG) findings, we sought to elucidate the potential factors related to sex disparities modulating treatment responses and sleep quality in RLS.
Maria P. Mogavero+9 more
wiley +1 more source
<i>Cdkl5</i> Knockout Mice Recapitulate Sleep Phenotypes of CDKL5 Deficient Disorder. [PDF]
Cao L+11 more
europepmc +1 more source
Summary Boosting slow‐wave activity (SWA) by modulating slow waves through closed‐loop auditory stimulation (CLAS) might provide a powerful non‐pharmacological tool to investigate the link between sleep and neurodegeneration. Here, we established mouse CLAS (mCLAS)‐mediated SWA enhancement and explored its effects on sleep deficits in neurodegeneration,
Inês Dias+5 more
wiley +1 more source
Central amygdala somatostatin neurons modulate stress-induced sleep-onset insomnia. [PDF]
Yao W+10 more
europepmc +1 more source