Results 81 to 90 of about 55,386 (306)

Bidirectional sleep‐seizure interactions and orexin in a mouse model of tuberous sclerosis complex‐related epilepsy

open access: yesEpilepsia, EarlyView.
Abstract Objective A strong bidirectional relationship exists between epilepsy and sleep, with seizures often occurring more frequently in sleep and, in turn, sleep being disrupted by seizures. However, the mechanistic basis of seizure–sleep interactions is poorly understood.
Nicholas R. Rensing   +4 more
wiley   +1 more source

Armodafinil-induced wakefulness in animals with ventrolateral preoptic lesions

open access: yes, 2014
Ramalingam Vetrivelan, Clifford B Saper, Patrick M Fuller Department of Neurology, Harvard Medical School and Beth Israel Deaconess Medical Center, Boston, MA, USA Abstract: Armodafinil is the pharmacologically active R-enantiomer of modafinil, a widely
Saper CB, Vetrivelan R, Fuller PM
core  

Evidence That Homeostatic Sleep Regulation Depends on Ambient Lighting Conditions during Wakefulness [PDF]

open access: yes, 2019
We examined whether ambient lighting conditions during extended wakefulness modulate the homeostatic response to sleep loss as indexed by. slow wave sleep (SWS) and electroencephalographic (EEG) slow-wave activity (SWA) in healthy young and older ...
Schlangen, Luc J.M.; id_orcid   +17 more
core   +1 more source

Unstable slow oscillations couple with epileptogenic fast‐rhythm bistability in sleep‐related epilepsy: A stereoelectroencephalographic study

open access: yesEpilepsia, EarlyView.
We examined the functional relationship between large‐scale δ‐band phase synchrony and local epileptogenic β–γ‐band amplitude bistability during NREM sleep. Increased synchrony and strong bistability characterized the epileptogenic zone, with strongest effects during N2 sleep, when seizures most frequently occur.
Gaia Burlando   +14 more
wiley   +1 more source

Sleep magnetoencephalography enhances detection and source imaging of seizures and fast oscillations in focal cortical dysplasia

open access: yesEpilepsia, EarlyView.
Abstract Objective Focal cortical dysplasia (FCD) causes drug‐resistant epilepsy requiring presurgical evaluation. Invasive electroencephalographic (EEG) studies demonstrate that sleep modulates epileptic activity, including interictal epileptiform discharges (IEDs), fast oscillations (FOs) in the beta (14–40 Hz) and gamma (40–80 Hz) frequency bands ...
Marcel Heers   +13 more
wiley   +1 more source

Functional Anatomy of the Sleep-Wakefulness Cycle: Wakefulness [electronic resource] /

open access: yes
Wakefulness is a necessary, active and periodic brain state, with a circadian and homeostatic regulation and precisely meshed with other states into the sleep-wakefulness cycle.
Reinoso-Suárez, Fernando.author.authttp://id.loc.gov/vocabulary/relators/aut   +3 more
core   +1 more source

Local Aspects of Sleep and Wakefulness

open access: yes, 2020
It is now well established that sleep and wakefulness are locally regulated. In fact, typical sleep hallmarks, such as slow waves and spindles, display a clear regional modulation based on maturational and experience-dependent brain plasticity.

core   +1 more source

Tissue oxygenation dynamics during transition from seizure to spreading depolarization in rat brain

open access: yesEpilepsia, EarlyView.
Abstract Objective Spreading depolarization (SD) is a phenomenon underlying various neurological conditions, including epilepsy. Researchers have suspected that local tissue oxygenation breakdown induces spontaneous SD. In this study, we investigated the relationship between spontaneous epileptic seizures and SD, with a focus on the role of local ...
Jiayang Liu, Bruce J. Gluckman
wiley   +1 more source

PARASOMNIAS – CURRENT STATE OF THE ISSUE

open access: yesЭпилепсия и пароксизмальные состояния, 2016
This article presents current views over the issue of parasomnias, and provides their classification including the awakening disorders, parasomnias linked to phase of fast sleep, and other parasomnias.
Ya. I. Levin
doaj  

The Wake of Wonder

open access: yesEcozon@: European Journal of Literature, Culture and Environment, 2019
     It is part of a sonnet sequence in seven parts, each a crown of sonnets. It explores the environmental crisis in a structured formal work.    
openaire   +3 more sources

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