Results 141 to 150 of about 1,032 (224)

Targeting Orexin 2 Receptors in Idiopathic Hypersomnia and Narcolepsy: A Randomised Phase 1b Proof‐Of‐Concept Study of Alixorexton

Journal of Sleep Research, EarlyView.
Orexin 2 receptor agonists have demonstrated that targeting the orexin system may address symptoms of central disorders of hypersomnolence. Results of this phase 1 study support the phase 2 clinical evaluation of oral alixorexton in patients with IH, NT2 and NT1.
Ronald R. Grunstein, Brendon J. Yee, Julia L. Chapman, Jian Eu Tai, Sheila Sivam, Craig Hopkinson, Daniel G. Smith, Alexandra Lovett, Shifang Liu, Sergey Yagoda, Bhaskar Rege   +10 more
wiley   +1 more source

Design and Simulation Study of a Jumping Takeoff Mechanism Inspired by the Hindleg Kinematics of Asian Migratory Locust, <i>Locusta migratoria</i>. [PDF]

Biomimetics (Basel)
Wang Y, Wang Y, Wang W, Shen H, Stamhuis EJ, Sun L, Wang Q, Liu C.   +7 more
europepmc   +1 more source

Resynchronisation of the Biological Clock Using Exposure to Low Oxygen Levels in Humans: An Exploratory Study

Journal of Sleep Research, EarlyView.
ABSTRACT Exposure to reduced oxygen levels occurs in several real‐world contexts, such as during air travel or altitude exposure, and emerging evidence suggests that hypoxia may interact with molecular pathways involved in circadian regulation. This exploratory study investigated the effects of normobaric hypoxia on circadian phase shifting in humans ...
Renée Morin, Geneviève Forest, Kim Isabelle‐Nolet, Vincent Bourgon, Félix‐Gabriel Duval, Jean‐François Mauger, Pascal Imbeault   +6 more
wiley   +1 more source

High-Efficiency Radiation via Fast Electron Beam Pinching in Nonuniform Plasmas. [PDF]

Research (Wash D C)
Zhu XL, Chen M, Sheng ZM.
europepmc   +1 more source

Electromagnetic counterparts to massive black-hole mergers. [PDF]

Living Rev Relativ, 2022
Bogdanović T, Miller MC, Blecha L.
europepmc   +1 more source

A Call to Action: Challenges and Future Directions for Sleep Health in Europe

Journal of Sleep Research, EarlyView.
ABSTRACT Sleep is fundamental to physical, cognitive, and emotional health and wellbeing. However, it is increasingly threatened by environmental, social, technological, and cultural pressures. To identify key priorities for improving sleep health across Europe, the European Sleep Research Society (ESRS)'s Equality, Diversity and Inclusion Committee ...
Fran Pilkington‐Cheney, Claire André, Seren Ucak, Raoua Ben Messaoud, Anna M. Biller, Inês Dias, Jose Prius Mengual, Daniela Noain, Michaela Pawley, Monisha Ravikumar, Matias Rusanen, Laura Stankeviciute, Adriana Michalak   +12 more
wiley   +1 more source

Weak prestorm submesoscale sea surface temperature gradients conducive to tropical cyclone intensification. [PDF]

Proc Natl Acad Sci U S A
Liu H, Cai W, Guan S, Wang G, Huang M, Wang H, Han Z, Zhang Z.   +7 more
europepmc   +1 more source

New insights into the mechanisms of ultrasonic emulsification in the oil-water system and the role of gas bubbles. [PDF]

Ultrason Sonochem, 2021
Wu WH, Eskin DG, Priyadarshi A, Subroto T, Tzanakis I, Zhai W.   +5 more
europepmc   +1 more source

Seeing the Speaker's Face Enhances Second Language Shadowing: Neural and Behavioral Evidence

Language Learning, EarlyView.
Abstract This functional magnetic resonance imaging (fMRI) study investigated how facial cues influence second language (L2) shadowing among 42 Japanese learners of English. Participants completed four conditions that varied by task type (listening vs. shadowing) and visual input (face vs. mosaic).
Hyeonjeong Jeong, Shuhei Kadota, Mayumi Kajiura, Hiroshi Nakanishi, Koji Kazai, Mariko Kawasaki, Yoko Nakano, Naoya Hase   +7 more
wiley   +1 more source

Kilometer-scale ocean processes behind the variability of the Island Mass Effect in the Maldives. [PDF]

Sci Rep
De Falco C, Bracco A, Desbiolles F, Pasquero C.   +3 more
europepmc   +1 more source