Results 41 to 50 of about 645,067 (303)

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Hospital Admission Profile of Neonates for Conditions Originating in the Perinatal Period in England and Wales Between 1999‒2020: An Ecological Study

International Journal of General Medicine, 2022
Hassan Al-shehri,1 Dania T Dahmash,2 Niels Rochow,3,4 Basma Alturki,5 Danah Alrajhi,5 Faisal Alayed,5 Faisal Alhazani,5 Hanan Alsuhibany,5 Abdallah Y Naser6 1Department of Pediatrics, College of Medicine, Imam Mohammad Ibn Saud Islamic University, Riyadh,
Al-shehri H, Dahmash DT, Rochow N, Alturki B, Alrajhi D, Alayed F, Alhazani F, Alsuhibany H, Naser AY   +8 more
doaj  

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

The impact of COVID-19 pandemic on trends in the recorded incidence of Long-Term Conditions identified from routine electronic health records between 2000 and 2021 in Wales: a population data linkage study.

International Journal of Population Data Science, 2022
Background The COVID-19 pandemic has resulted in delayed diagnosis and treatment for cancer patients and increases in elective surgery waiting lists. The impact on other ‘long-term’ conditions (LTCs) is unclear. We examined the effects of the pandemic on
Cathy Qi, Tim Osborne, Rowena Bailey, Joe Hollinghurst, Ashley Akbari, Alison Cooper, Ruth Crowder, Holly Peters, Rebecca-Jane Law, Anthony Davies, Ruth Lewis, Mark Walker, Adrian Edwards, Ronan Lyons   +13 more
doaj   +1 more source

A nationwide student survey on biochemistry learning resources in Italy

FEBS Open Bio, EarlyView.
We conducted a survey among Italian university students to investigate their preferred study materials for biochemistry. We then analyzed the collected data to identify these materials. This information may be valuable to the Biochemistry educational community. The graphical abstract was created with Claude (Opus 5.5; Anthropic, 2026).
Anna Marabotti, Ivano Eberini, Maria Luisa Genova, Francesca Mensitieri, Francesco Malatesta   +4 more
wiley   +1 more source

Farm Tourism in Wales. Products and Markets, Resources and Capabilities. The Experience of Six Farm Tourism Operators

European Countryside, 2013
Wales’ high quality natural environment is a key attraction for tourists from more urban parts of the UK and this has provided opportunities for many farmers to diversify into tourism.
Talbot Mandy
doaj   +1 more source

Coronavirus «Strengthened» the Autonomy of British Regions [PDF]

Научно-аналитический вестник Института Европы РАН, 2020
The United Kingdom turned out to be unprepared for the rapid spread of the COVID-19 epidemic and already in early May 2020 took second place in the world after the United States in the number of deaths from it. B.
Oleg Okhoshin
doaj   +1 more source

Integration of Serum Neurofilament Light Chain and Cortical Dysfunction Improves Diagnostic Accuracy in ALS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine whether integration of serum neurofilament light chain (NfL) and cortical dysfunction improves diagnostic accuracy in amyotrophic lateral sclerosis (ALS) when applied alongside the Gold Coast criteria (GCC). Methods In this prospective study, 148 participants with suspected ALS were recruited (101 ALS and 47 with ALS ...
Aicee Dawn Calma, Nathan Pavey, Yukiko Tsuji, Amirul Ab Ghapar, Mehdi A.J. van den Bos, Bronwen Orden, Grace Lee, Linda Mekhael, Julie Ryder, Cláudia Santos Silva, David McDonald, Fakhria Kakar, Con Yiannikas, Matthew C. Kiernan, David A. Brown, Parvathi Menon, Steve Vucic   +16 more
wiley   +1 more source

Factors Associated With Fibromyalgia Diagnosis Among People Meeting Criteria: Results From UK Biobank

Arthritis Care &Research, EarlyView.
Objective The diagnosis of fibromyalgia (FM) is challenging due to the absence of definitive biomarkers, numerous overlapping comorbidities, and its reliance on patient‐reported symptoms. Discrepancies between diagnostic criteria and clinical practice imply the possibility of diagnostic biases, complicating timely and accurate identification.
Sung‐A Kim, Gary J. Macfarlane, Marcus J. Beasley   +2 more
wiley   +1 more source

Songs and Identity in Welsh Patagonia [PDF]

Studia Ethnologica Pragensia, 2023
Over the centuries there have been a number of attempts, for economic, political and religious reasons, to create Welsh settlements overseas. The most successful of these, in terms of longevity at least, and perhaps the best known of all Welsh emigration
E. Wyn James
doaj