Results 31 to 40 of about 8,102 (257)
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
A Model for Assessing the Level of Walkability in Urban Neighborhoods in Sri Lanka
International Journal of Built Environment and Sustainability, 2015 The quality of the neighboring environment plays a major role in encouraging people to walk when attending their daily needs. Although past studies have identified a relationship between neighborhood design factors and the level of walkability, this ...
Gayani Ranasinghe +4 more
doaj +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Associations of neighbourhood walkability indices with weight gain
International Journal of Behavioral Nutrition and Physical Activity, 2018 Background Inconsistent associations of neighbourhood walkability with adults’ body weight have been reported. Most studies examining the relationships of walkability and adiposity are cross-sectional in design. We examined the longitudinal relationships
Mohammad Javad Koohsari +6 more
doaj +1 more source
Transportation Research Interdisciplinary Perspectives, 2022 The City of Jakarta has changed the paradigm of transportation development policy in order to prioritize pedestrians. This research aims to examine the walkability of Sudirman-Thamrin central business district.
Agah Muhammad Mulyadi +4 more
doaj +1 more source
Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer
Aging and Cancer, EarlyView.Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss +12 more
wiley +1 more source
Development of a contextualized spatial network–based walkability (CSNW) index
International Journal of Urban Sustainable DevelopmentToday, walkability is a priority in urban planning worldwide due to its positive impact on promoting sustainable cities. Although numerous studies have assessed walkability using various indices, they do not capture pedestrian needs, nor account for ...
Abdullh Banger +3 more
doaj +1 more source
What Features of the Street Influence Visual Walkability? An Innovative Approach Using Cinematic Virtual Reality [PDF]
ISPRS Annals of the Photogrammetry, Remote Sensing and Spatial Information SciencesWe present a new method for assessing visual walkability using 360° videos and an eye-tracking in Cinematic Virtual Reality (CVR). Visual walkability refers to the walkability perceived by pedestrians through visual stimuli in the urban environment ...
C. Wang +4 more
doaj +1 more source
Frontiers of Architectural Research, 2023 This study develops a holistic approach that underlines the effect of spatial, behavioral, and perceptional dimensions on walkability at the neighborhood scale.
Ozge Ceylin Yıldırım +2 more
doaj +1 more source
Five‐Year Disease Progression in Synuclein Seeding Positive Sporadic Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To provide a comprehensive description of disease progression in synuclein seeding assay (SAA) positive sporadic Parkinson Disease participants, using Neuronal Synuclein Disease integrated biological and functional impairment staging framework.
Paulina Gonzalez‐Latapi +19 more
wiley +1 more source