Lessons Learned From a Delayed‐Start Trial of Modafinil for Freezing of Gait in Parkinson's Disease
ABSTRACT Objective Freezing of gait (FOG) in people with Parkinson's disease (PwPD) is debilitating and has limited treatments. Modafinil modulates beta/gamma band activity in the pedunculopontine nucleus (PPN), like PPN deep brain stimulation. We therefore tested the hypothesis that Modafinil would improve FOG in PwPD.
Tuhin Virmani +8 more
wiley +1 more source
Mobility and Walkability: An Analysis OF Urban Design Elements around Divisoria, Cagayan de Oro
Mobility and Walkability is an important concept in urban planning. The term is built around the concept of providing healthy communities, reducing dependency on automobiles and improving health consciousness to people.
Ar. Romel Eltanal
doaj +1 more source
Variably Protease‐Sensitive Prionopathy: Two New Cases With Motor Neuron‐Dementia Syndrome
ABSTRACT We describe two patients with variably protease‐sensitive prionopathy (VPSPr) who developed progressive upper motor neuron symptoms, insomnia, behavioral and cognitive decline, compatible with primary lateral sclerosis associated with frontotemporal dementia (FTD).
María Elena Erro +10 more
wiley +1 more source
Background Individual-level studies support a positive relation between walkable built environments and participation in moderate-intensity walking. However, the utility of this evidence for population-level planning is less clear as it is derived at ...
Darren J. Mayne +3 more
doaj +1 more source
Interactions between neighborhood social environment and walkability to explain Belgian older adults' physical activity and sedentary time [PDF]
This study examined associations between neighborhood social factors and physical activity (PA) and sedentary behavior (SB) in older adults. Furthermore, possible moderating effects of neighborhood walkability were explored.
De Bourdeaudhuij, Ilse +5 more
core +3 more sources
Predicting Loss of Ambulation in Limb Girdle Muscular Dystrophy R9
ABSTRACT Background Limb girdle muscular dystrophy type R9 (LGMDR9) results from biallelic variants in FKRP. There is limited data to predict loss of ambulation (LOA) among those with LGMDR9. Methods Participants in an ongoing dystroglycanopathy natural history study (NCT00313677) with FKRP variants who had achieved ambulation and were more than 3 ...
Chandra L. Miller +6 more
wiley +1 more source
Impact of Neighborhood Urban Morphologies on Walkability Using Spatial Multi-Criteria Analysis
With the increase in car domination, air pollution, traffic congestion, and urban sprawl, sustainable, livable, creative, and walkable cities are critical, now more than ever, for improving quality of life.
Sara Ibrahim +2 more
doaj +1 more source
Pasos Hacia La Salud: a randomized controlled trial of an internet-delivered physical activity intervention for Latinas. [PDF]
BackgroundInternet access has grown markedly in Latinos during the past decade. However, there have been no Internet-based physical activity interventions designed for Latinos, despite large disparities in lifestyle-related conditions, such as obesity ...
Bock, Beth C +11 more
core +3 more sources
Whole‐Body Pattern of Muscle Degeneration and Progression in Sarcoglycanopathies
ABSTRACT Objective To characterize whole‐body intramuscular fat distribution pattern in patients with sarcoglycanopathies and explore correlations with disease severity, duration and age at onset. Methods Retrospective, cross‐sectional, multicentric study enrolling patients with variants in one of the four sarcoglycan genes who underwent whole‐body ...
Laura Costa‐Comellas +39 more
wiley +1 more source
Assessing Walkability in Sulaimani City Center
Walkability within urban design and planning context refers to urban environments that are friendly and supportive for the pedestrian. Walkable environments offer many economic, social, health, and environmental benefits and contribute to UN Sustainable ...
Roza Abdullatif Radha +2 more
doaj +1 more source

