Results 101 to 110 of about 661,915 (309)

Onasemnogene Abeparvovec in Patients With SMA: Interim Results of the RESTORE Registry in Japan

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective There are limited real‐world data regarding the safety and effectiveness of onasemnogene abeparvovec (OA; Zolgensma) infusion, a one‐time gene replacement therapy, for Japanese patients with spinal muscular atrophy (SMA). We aimed to improve understanding of the real‐world outcomes for OA in Japan.
Kayoko Saito, Kamal Benguerba, Ken Tsuchida, Kazushige Yazawa, Isao Tsumiyama, Hiromitsu Kayama, Sandra P. Reyna, Farid Khan, Richard S. Finkel   +8 more
wiley   +1 more source

Representation and exposition: being and walking along the designs of Boulevard 24 de Mayo in Quito, Ecuador (1991-2012)

ARQUISUR Revista
The present study reflects on the last two urban-architectural proposals in Boulevard 24 de Mayo in Quito, Ecuador, which were developed in 1991 and 2012, respectively. We aim at identifying the conditions of being and walking along that urban space with
Kléver Francisco Vásquez Vargas
doaj   +1 more source

Understanding walking and cycling : summary of key findings and recommendations [PDF]

, 2011
It is widely recognized that there is a need to increase levels of active and sustainable travel in British urban areas. The Understanding Walking and Cycling (UWAC) project, funded by the EPSRC, has examined the factors influencing everyday travel ...
Tight, Miles, Jopson, Ann, Scheldeman, Griet, Jones, Tim, Pooley, Colin, Strano, Emanuele, Horton, David, Mullen, Caroline, Chisholm, Alison, Constantine, Sheila   +9 more
core  

Do walking strategies to increase physical activity reduce reported sitting in workplaces: A randomized control trial [PDF]

, 2009
Background Interventions designed to increase workplace physical activity may not automatically reduce high volumes of sitting, a behaviour independently linked to chronic diseases such as obesity and type II diabetes.
Burton, Nicola W., Cooke, CB, Puig-Ribera, Anna, Burton, NW, Gilson, Nicolas D., Nicholas D Gilson, McKenna, J, Nicola W Burton, Gilson, N., Puig Ribera, Anna, Gilson Nicholas D, McKenna Jim, Wendy J Brown, Gilson, Nicholas D, Gilson, Nicholas D., Brown Wendy J, McKenna, J., Cooke Carlton B, Puig-Ribera, A, Cooke, Carlton B., Burton Nicola W, Brown, WJ, Brown, Wendy J., Brown, W., Burton, N., Puig-Ribera Anna, Gilson, ND, Anna Puig-Ribera, Puig-Ribera, A., Carlton B Cooke, Jim McKenna, McKenna, Jim   +31 more
core   +1 more source

Prominent Movement Disorders in RNU2‐2‐Related Spliceosomopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Pediatric movement disorders often overlap with neurodevelopmental diseases, suggesting shared molecular mechanisms. Variants in small nuclear RNA (snRNA) genes encoding spliceosome components have recently been associated with neurodevelopmental disorders, termed “RNUopathies.” We analyzed genome sequencing data from 14 patients with ...
Magdalena Krygier, Ugo Sorrentino, Matias Wagner, Marta Zawadzka, Anna Lemska, Maria Mazurkiewicz‐Bełdzińska, Michael Zech   +6 more
wiley   +1 more source

Walking the Walk [PDF]

Cell, 2002
Traver, David, Zon, Leonard I.
openaire   +2 more sources

Relationships between Physical Activity, Sleeping Time, and Psychological Distress in Community-Dwelling Elderly Japanese

Medicina, 2019
Background and objectives: It is well-known that lifestyle is closely associated with psychological distress in many elderly subjects. However, the effect of intervention with physical activity and/or sleeping on psychological distress has not been fully
Yukio Yamamoto, Hiromi Suzuki, Yutaka Owari, Nobuyuki Miyatake   +3 more
doaj   +1 more source

Random walk on random walks

Electronic Journal of Probability, 2015
42 pages, 6 ...
Hilário, M.R., Hollander, W.T.F. den, Santos, R.S., Sidoravicius, V., Teixeira, A.   +4 more
openaire   +8 more sources

A Qualitative Analysis of Patient Perspectives and Preferences in Lupus Management to Guide Lupus Guidelines Development

Arthritis Care &Research, EarlyView.
Objective A patient‐centered approach for chronic disease management, including systemic lupus erythematosus (SLE), aligns treatment with patients’ values and preferences, leading to improved outcomes. This paper summarizes how patient experiences, perspectives, and priorities informed the American College of Rheumatology (ACR) 2024 Lupus Nephritis (LN)
Shivani Garg, Izzy Hartel, Lisa R. Sammaritano, Anca Askanase, Bonnie L. Bermas, Maria Dall'Era, Alí Duarte‐García, Victoria P. Werth, Brad Rovin, Reem A. Mustafa, Amy S. Turner, Bené Williams, Brian L. Ung, Hiya Bhavsar, Monique C. Gore‐Massy, Nahirannette Pulido, Natacha Guerrero, Natalie M. Smith, Wambui Machua, Linda T. Hiraki, Mary Beth Son   +20 more
wiley   +1 more source

Design and Evaluation of Dynamic Movement Orthosis on Functional Parameters in a Child With Spastic Diplegia Cerebral Palsy [PDF]

Journal of Rehabilitation
Objective Cerebral palsy (CP) is the most prevalent motor disability during childhood, characterized by a range of movement and posture disorders that result in activity limitations.
Sedigheh Sadat Mirbagheri, Gholamreza Aminian, Mahmood Bahramizadeh, Hamid Dalvand, Farzam Farahmand, Mohsen Vahedi   +5 more
doaj