Results 71 to 80 of about 2,108,401 (400)

Mitochondrial DNA disorders in neuromuscular diseases in diverse populations

Annals of Clinical and Translational Neurology, EarlyView.
Abstract Neuromuscular features are common in mitochondrial DNA (mtDNA) disorders. The genetic architecture of mtDNA disorders in diverse populations is poorly understood. We analysed mtDNA variants from whole‐exome sequencing data in neuromuscular patients from South Africa, Brazil, India, Turkey and Zambia. In 998 individuals, there were two definite
Fei Gao, Katherine R Schon, Jana Vandrovcova, Özlem Yayıcı Köken, Sharika Raga, Kireshnee Naidu, Maryke Schoonen, Nimita Rani, Pedro Tomaselli, Dipti Baskar, Musambo Kapapa, Ipek Polat, Lindsay A Wilson, Kumarasamy Thangaraj, Uluç Yiş, Bevinahalli N Nandeesh, David Bearden, Michelle Kvalsund, Franclo Henning, Seena Vengalil, Atchayaram Nalini, Claudia F. R. Sobreira, Wilson Marques, Haluk Topoloğlu, Michael G Hanna, Sireesha Yareeda, Venugopalan Y Vishnu, Francois H van der Westhuizen, Izelle Smuts, Surita Meldau, Jo Wilmshurst, Büşranur Çavdarlı, Jeannine Heckmann, Patrick F Chinnery, Rita Horvath   +34 more
wiley   +1 more source

Comparing 16 Different Dual–Tasking Paradigms in Individuals With Multiple Sclerosis and Healthy Controls: Working Memory Tasks Indicate Cognitive–Motor Interference

Frontiers in Neurology, 2020
Background: Cognitive–motor interference (CMI) is measured by dual-tasking (DT), which involves motor and cognitive tasks. There is no consensus as to whether CMI is present in multiple sclerosis (MS).Objectives: We investigated the effects of 16 DT ...
Carmela Leone, Lousin Moumdjian, Lousin Moumdjian, Francesco Patti, Ellen Vanzeir, Ilse Baert, Renee Veldkamp, Bart Van Wijmeersch, Bart Van Wijmeersch, Peter Feys   +9 more
doaj   +1 more source

To Walk or Not to Walk? The Hierarchy of Walking Needs [PDF]

Environment and Behavior, 2005
The multitude of quality of life problems associated with declining walking rates has impelled researchers from various disciplines to identify factors related to this behavior change. Currently, this body of research is in need of a transdisciplinary, multilevel theoretical model that can help explain howindividual, group, regional, and physical ...
openaire   +2 more sources

Validity of the activPAL3 activity monitor in people moderately affected by Multiple Sclerosis [PDF]

, 2017
Background: Walking is the primary form of physical activity performed by people with Multiple Sclerosis (MS), therefore it is important to ensure the validity of tools employed to measure walking activity.
Algie, K., Coulter, E. H., Freeman, J., Mattison, P.G., McConnachie, A., McCorkell, S., McGuire, C., Miller, L., Paul, L., Weller, B., Wu, O.   +10 more
core   +4 more sources

Compound Heterozygous MRPS14 Variants Associated With Leigh Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT MRPS14 (uS14m) is a nuclear‐encoded ribosomal protein important for mitochondria‐specific translation. To date, only a single individual with a recessive MRPS14‐related disorder (also known as COXPD38) has been reported. We report an additional subject possessing novel compound heterozygous MRPS14 variants (p.Asp37Asn, p.Asn60Asp). The subject
Maria Gabriela Otero, Christina Freeman, Ruchi Shah, Renkui Bai, Hong Cui, Marian Castro, Zachary Myers, Eric Choy, Derek Chan, Molly Easter, Sophia Y. Zhao, Madeline Babros, Ruchi Garg, Matthew Deardorff, Franklin Moser, Tyler Mark Pierson   +15 more
wiley   +1 more source

Fertility care in low- and middle-income countries

Reproduction and Fertility
Infertility affects millions worldwide, with significant medical, financial, and emotional challenges, particularly in low- and middle-income countries (LMICs).
Willem Ombelet, Federica Lopes
doaj   +1 more source

Actionable Wearables Data for the Neurology Clinic: A Proof‐of‐Concept Tool

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Wearable devices can monitor key health and fitness domains. In multiple sclerosis (MS), monitoring step count and sleep is feasible, valid, and offers a holistic glimpse of patient functioning and worsening. However, data generated from wearables are typically unavailable at the point of care.
Nicolette Miller, Ebenezer Chinedu‐Eneh, Jaeleene Wijangco, Kyra Henderson, Nikki Sisodia, Narender Sara, Jennifer Reihm, Shane Poole, Jim Rowson, Chu‐Yueh Guo, Jeffrey M. Gelfand, Valerie J. Block, Riley Bove   +12 more
wiley   +1 more source

Is every-day walking in older adults more analogous to dual-task walking or to usual walking? Elucidating the gaps between gait performance in the lab and during 24/7 monitoring

European Review of Aging and Physical Activity, 2019
BackgroundThe traditional evaluation of gait in the laboratory during structured testing has provided important insights, but is limited by its “snapshot” character and observation in an unnatural environment.
I. Hillel, Eran Gazit, A. Nieuwboer, L. Avanzino, L. Rochester, A. Cereatti, U. D. Croce, M. Rikkert, B. Bloem, E. Pelosin, S. Del Din, Pieter Ginis, Nir Giladi, A. Mirelman, Jeffrey M. Hausdorff   +14 more
semanticscholar   +1 more source

Pattern Generation for Walking on Slippery Terrains

, 2017
In this paper, we extend state of the art Model Predictive Control (MPC) approaches to generate safe bipedal walking on slippery surfaces. In this setting, we formulate walking as a trade off between realizing a desired walking velocity and preserving ...
Herzog, Alexander, Khadiv, Majid, Moosavian, S. Ali A., Righetti, Ludovic   +3 more
core   +1 more source

Using pedometers as motivational tools : are goals set in steps more effective than goals set in minutes for increasing walking? [PDF]

, 2008
Background Pedometers are popular devices that measure walking steps. There has been a recent surge in promoting the pedometer as a motivational tool to increase walking. However, little empirical evidence exists to support this suggestion.
Baker, Graham, Lowry, Ruth, Mutrie, Nanette   +2 more
core   +2 more sources