Results 51 to 60 of about 2,027,681 (247)

Programmable Microgel Degradation in Dynamic Granular Hydrogels Guides Extracellular Matrix Assembly During Tissue Repair

Advanced Materials, EarlyView.
This study reports on the chemical modification of hyaluronic acid to create hydrogels with hydrolytic degradability ranging from 2–28 days. Granular hydrogels that undergo timed degradation to increase porosity enhance cell invasion and provisional ECM remodeling in a muscle injury model, leading to reduced fibrosis and improved regeneration ...
Zhiyuan Chen, Tuba Marjan, Xinyue Lu, Nicole E. Mertens, Keira Vesy, Dean E. Stornello, James F. Markworth, Taimoor H. Qazi   +7 more
wiley   +1 more source

Endorotor-Based Endoscopic Necrosectomy as a Rescue or Primary Treatment of Complicated Walled-off Pancreatic Necrosis. A Case Series [PDF]

, 2020
Direct endoscopic necrosectomy (DEN) is a cumbersome, time-consuming procedure that can be necessary in cases of infected pancreatic walled-off necrosis (WON) not responding to endoscopic ultrasound (EUS)- guided drainage only.
Gasbarrini A., Larghi A., Rizzatti G., Costamagna G., Impagnatiello M., Mihai Rimbas, Antonio Gasbarrini, Alberto Larghi, Michele Impagnatiello, Gianenrico Rizzatti, Guido Costamagna   +10 more
core   +1 more source

Comparative outcomes of endoscopic ultrasound–guided cystogastrostomy for peripancreatic fluid collections: a systematic review and meta-analysis

Therapeutic Advances in Gastrointestinal Endoscopy, 2019
Background: Endoscopic ultrasound–guided cystogastrostomy has become the first-line treatment for symptomatic peripancreatic fluid collections. The aim of this study is to analyze the efficacy and safety of cystogastrostomy via a meta-analysis of the ...
Benjamin D. Renelus, Daniel S. Jamorabo, Hashroop K. Gurm, Niel Dave, William M. Briggs, Mukul Arya   +5 more
doaj   +1 more source

Effect of Early Continuous Veno-Venous Haemofiltration in Severe Acute Pancreatitis for the Prevention of Local Pancreatic Complications

Gastroenterology Research and Practice, 2022
Objective. To compare the conventional treatment and continuous veno-venous haemofiltration (CVVH) in severe acute pancreatitis (SAP) for the prevention of pseudocyst and walled-off necrosis. Patients and Methods. Forty-two patients were divided into two
Satish Chandra Yadav, Bingqiang Zhang
doaj   +1 more source

Recent Advances in Light‐Addressable Electrochemistry for Spatially Resolved Applications

Advanced Materials Technologies, EarlyView.
This comprehensive review highlights light‐addressable electrochemistry as a powerful tool that uses light to control localized chemical reactions on unstructured semiconductor surfaces. The work evaluates advanced strategies to optimize electrode materials for enhanced spatial resolution and stability. Furthermore, it showcases diverse applications in
Nhi Trang Vo, Sina Jamali, Nam‐Trung Nguyen   +2 more
wiley   +1 more source

Intelligent Micro/Nanorobots for Targeted Interventional Therapy: From Bench to Clinic

Advanced Robotics Research, EarlyView.
Zirui Zhang et al. reviewed the application and challenges of mobile nanomachines in interventional therapy. By converting exogenous energy, including chemical, magnetic, optical, and ultrasonic sources, into mechanical forces, micro/nanorobots (MNRs) enable precise actuation at unprecedented scales. Evolving far beyond traditional drug delivery, these
Zirui Zhang, Yu Dong, Yongsheng Du, Rui Gao, Lin Zhang, Fei Tong   +5 more
wiley   +1 more source

Endoscopic versus laparoscopic drainage of pseudocyst and walled-off necrosis following acute pancreatitis: a randomized trial

, 2020
Background: Pancreatic fluid collections (PFC) may develop following acute pancreatitis (AP). Endoscopic and laparoscopic internal drainage are accepted modalities for drainage of PFCs but have not been compared in a randomized trial.
Babu, Divya, Bansal, Virinder Kumar, Misra, Mahesh Chandra, Kumar, Subodh, Dhingra, Rajan, Meena, Danishwar, Garg, Pramod Kumar, Padhan, Rajesh Kumar, Krishna, Asuri   +8 more
core   +1 more source

Open necrosectomy in acute pancreatitis–obsolete or still useful?

World Journal of Emergency Surgery, 2020
Background Multiple organ failure and early surgery are associated with high morbimortality after open necrosectomy. Data are mostly derived from historical cohorts with early necrosectomy bereft of step-up treatment algorithm implementation.
Henrik Leonard Husu, Jouni Antero Kuronen, Ari Kalevi Leppäniemi, Panu Juhani Mentula   +3 more
doaj   +1 more source

Magnetically Actuated Microrobot for Drug Delivery: Current Progress and Challenges

Advanced Robotics Research, EarlyView.
Magnetically actuated microrobots are reshaping targeted drug delivery through wireless propulsion, programmable materials, and localized therapeutic release. This review examines how fabrication, body material selection, structural architecture, loading mechanisms, and imaging‐guided control converge to enable microrobotic therapies while identifying ...
Yang Yang, David J. Cappelleri
wiley   +1 more source

Disrupted TFEB/GDNF–cAMP/ATP Coupling Underlies Astrocytic Dysfunction and Depression in LRRK2 G2019S Parkinson's Mice

Advanced Science, EarlyView.
ABSTRACT The LRRK2 G2019S mutation, a Parkinson's disease–linked variant, has been associated with depression‐like phenotypes, but mechanisms remain unclear. We chart age‐dependent behavioral changes and astrocyte reactivity in G2019S mice and define a pathway connecting LRRK2 to TFEB/GDNF signaling, cellular energetics, and inflammation.
Longping Yao, Maryam Hatami, Sumeyye Koc, Qing Jiang, Thomas Skutella, Yuanfeng Zhang   +5 more
wiley   +1 more source