Results 111 to 120 of about 2,027,729 (286)

Intrasplenic Thymus Organogenesis from Injectable Tissue Fragments Restores Functional T‐Cell Immunity

Advanced Science, EarlyView.
Clinical intramuscular thymus transplantation yields only short‐lived efficacy and marginal therapeutic benefits. Benefiting from the spleen's intrinsic strengths—rapid vascular perfusion, abundant developmental factors, and resident progenitors—the intrasplenic thymic grafts achieve robust thymic regeneration and substantial T‐cell reconstitution ...
Shaocong Wang, Zijian Zhang, Fulin Dai, Zhijie Yin, Zhen Xing, Yurong Li, Haochong Lei, Junfeng Zhang, Chunyan Liu, Yan Li, Lei Dong   +10 more
wiley   +1 more source

Endoscopic “Step‑up” Treatment Approach for Walled off Pancreatic Necrosis

Journal of Digestive Endoscopy, 2017
Surinder Singh Rana, Sobur Uddin Ahmed
doaj   +1 more source

SerpinA3 is an Endogenous TGF‐β Receptor Antagonist that Attenuates Cardiac Fibroblast Activation and Fibrotic Remodeling

Advanced Science, EarlyView.
SerpinA3 acts as an endogenous TGF‐β receptor antagonist that binds to the extracellular domain of TGFR‐1, thereby preventing TGFR‐1–TGFR‐2 complex formation. This receptor‐level blockade suppresses TGF‐β/Smad2/3 signaling, attenuates cardiac fibroblast activation, and extracellular matrix deposition, and ultimately alleviates pressure overload–induced
Hui Wang, Jieyu Cui, Chunlu Huang, Wanyi Guo, Tong Liu, Yi Zhu, Shuai Shao, Kangyin Chen, Jinlong He, Qiankun Bao   +9 more
wiley   +1 more source

Endoscopic management of symptomatic walled-off omental fat necrosis

VideoGIE, 2020
C. Roberto Simons-Linares, MD, David E. Long, MD, Prabhleen Chahal, MD   +2 more
doaj   +1 more source

Indocyanine green-guided laparoendoscopic treatment of walled-off pancreatic necrosis

Revista de Gastroenterología de México (English Edition), 2022
R.D. Brito-Carmona, A. Cuendis-Velázquez, A.F. Chávez-Hernández, A.D. Galván-Cruz, L.E. Cárdenas-Lailson   +4 more
doaj   +1 more source

THSD7A Exacerbates Atherosclerosis via Activation of Signaling Axis αvβ3/CEBPD/IL1A

Advanced Science, EarlyView.
THSD7A exerts pro‐inflammatory effects and exacerbates atherosclerosis. Mechanistically, THSD7A regulates endothelial cell inflammation and atherosclerosis by activating the αvβ3/CEBPD/IL1A signaling axis. THSD7A is not only a genetic marker but also a potential therapeutic target for coronary artery disease (CAD).
Jiankun Liu, Hongfei Liu, Yiqi Wan, Andong Wu, Jiayu Qiu, Xueting Gong, Ya Zhao, Yuanyuan Li, Bingbing Zhou, Yangyi Zheng, Fang Wu, Yuanzheng Zhu, Weixin Lv, Xueer Li, Qiang Yuan, Xiao‐Li Tian   +15 more
wiley   +1 more source

Endoscopic necrosectomy under fluoroscopic guidance during transmural drainage of walled-off pancreatic necrosis (WOPN) [PDF]

, 2020
Introduction: The endoscopic treatment of walled-off pancreatic necrosis (WOPN) as well as other minimally invasive methods have been evolving since last years.
Jagielski, Mateusz, Jackowski, Marek, Adrych, Krystian, Smoczyński, Marian, Sztuczka, Ewa   +4 more
core  

Enteric ChAT‐Expressing Neurons Mediate the Protective Effect of Lactobacillus plantarum in Inflammatory Bowel Disease

Advanced Science, EarlyView.
In colitis patients and mice, reduced Lactobacillus abundance is observed. Experimental studies show that L. plantarum A736 metabolizes dietary tryptophan into indole‐3‐lactic acid (ILA), while both L. plantarum A736 and ILA impact ChAT‐expressing enteric neurons and acetylcholine levels, thereby regulating intestinal immune responses and alleviating ...
Bing Xia, Yuwei Sun, Jialin Wang, Yike Liu, Lu Wang, Shiqi Jiang, Gaiyan Bai, Ruijing Zhang, Yu Zhang, Rongwei Kou, Danna Wang, Beita Zhao, Junjie Yi, Yu Fu, Xiaoning Liu, Xuebo Liu   +15 more
wiley   +1 more source

ROBOT-ASSISTED TRANS-GASTRIC DRAINAGE AND DEBRIDMENT OF WALLED-OFF PANCREATIC NECROSIS USING THE ROBOTIC ENDOWRIST® STAPLER FOR THE DA VINCI XI®

, 2018
Introduction: Walled-off pancreatic necrosis (WOPN) represents a late complication of severe acute pancreatitis, with a high mortality rate. Its management depends on the patient's symptoms and WOPN location.
Gianardi D, Di Candio G, Picchi M, Bianchini M, Mosca F, Morelli L, Palmeri M, Guadagni S, Furbetta N, Di Franco G   +9 more
core  

Metal stent and percutaneous endoscopic necrosectomy as dual approach for the management of complex walled-off pancreatic necrosis

Pancreatic fluid collections (PFCs) are one of the local complications of acute pancreatitis and include walled-off pancreatic necrosis (WOPN), which are complex entities with challenging management. The infection of pancreatic necrosis leads to a poorer
Fabbri S., Fabbri C., Giuffrida P., Binda C., Gibiino G., Giampalma E., Vizzuso A., Coluccio C., Perini B.   +8 more
core   +1 more source