Results 161 to 170 of about 1,205,693 (325)

The Effect of the Gem‐Dimethyl Unit in the Gold‐Catalyzed Cycloisomerization of Aliphatic 1‐Bromoalkynes

European Journal of Organic Chemistry, EarlyView.
The conformational effect of the gem‐dimethyl motif and its isostere cyclopropane unit in the gold‐catalyzed cycloisomerization of aliphatic 1‐bromoalkynes has been studied. An unexpected inhibitory effect of the cyclopropane ring has been observed.
Rubén Miguélez, Omar Arto, Hanna Siera, Isabel Merino, Gebhard Haberhauer, Pablo Barrio   +5 more
wiley   +1 more source

Severity of effect considerations regarding the use of mutation as a toxicological endpoint for risk assessment: A report from the 8th International Workshop on Genotoxicity Testing (IWGT)

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Exposure levels without appreciable human health risk may be determined by dividing a point of departure on a dose–response curve (e.g., benchmark dose) by a composite adjustment factor (AF). An “effect severity” AF (ESAF) is employed in some regulatory contexts.
Barbara L. Parsons, Marc A. Beal, Kerry L. Dearfield, George R. Douglas, Min Gi, B. Bhaskar Gollapudi, Robert H. Heflich, Katsuyoshi Horibata, Michelle Kenyon, Alexandra S. Long, David P. Lovell, Anthony M. Lynch, Meagan B. Myers, Stefan Pfuhler, Alisa Vespa, Andreas Zeller, George E. Johnson, Paul A. White   +17 more
wiley   +1 more source

Outcome of IWGT workshop on transcriptomic biomarkers for genotoxicity: Key considerations for bioinformatics

Environmental and Molecular Mutagenesis, EarlyView.
Abstract As a part of the International Workshop on Genotoxicity Testing (IWGT) in 2022, a workgroup was formed to evaluate the level of validation and regulatory acceptance of transcriptomic biomarkers that identify genotoxic substances. Several such biomarkers have been developed using various molecular techniques and computational approaches. Within
Matthew J. Meier, Florian Caiment, J. Christopher Corton, Roland Frötschl, Yurika Fujita, Danyel Jennen, Roman Mezencev, Carole Yauk   +7 more
wiley   +1 more source

Characterization of Fatty Acid Profiles and Nutritional Quality Indices in Commercial Spreadable Processed Cheeses: Comparative Analysis and Health Implications

Food Safety and Health, EarlyView.
Natural processed cheeses showed a more favorable nutritional profile, including higher unsaturated fatty acids and better functional performance. A balanced fatty acid composition was identified as a key factor influencing meltability, oil separation, and overall quality of processed cheeses.
Shaimaa M. Hamdy, Amr A. Metwally, Mahmoud A. Deghedie, Hani S. Abdelmontaleb   +3 more
wiley   +1 more source

Reply to Compton et al.: Another paradoxical misunderstanding. [PDF]

Proc Natl Acad Sci U S A
Butler G, Baker J, Amend SR, Pienta KJ, Venditti C.   +4 more
europepmc   +1 more source

Material ESG Performance and Bid Premium in Merger and Acquisition Deals

International Journal of Finance &Economics, EarlyView.
ABSTRACT This study examines the firm‐level and country‐level environmental, social, and governance (ESG) performance on bid premiums in cross‐border mergers and acquisitions (M&A) transactions. We document considerable variations in bid premiums. Higher carbon emissions are associated with higher bid premiums, suggesting that acquirers may perceive ...
Ndubuisi Ezenwa, Ibrahim Ayoade Adekunle, Robin Maialeh   +2 more
wiley   +1 more source

Safety and efficacy of an extravascular implantable cardioverter-defibrillator in a child: A case report. [PDF]

HeartRhythm Case Rep
Ryan C, Linnane N, Walsh M, Walsh KP.
europepmc   +1 more source

Time Out: A Scoping Review of Non‐Duration Based Social Media Use Measures and Adolescent Mental Health

Journal of Adolescence, EarlyView.
ABSTRACT Introduction Research to understand the role of social media use (SMU) in explaining deteriorating adolescent mental health has been limited by broad, nonspecific measures of social media use, specifically ‘time spent on social media’. These measures provide insufficient detail to capture specific risk and protective factors to users.
Amanda M. Sursely, Bengi Baran, Gerta Bardhoshi, Jonathan M. Platt   +3 more
wiley   +1 more source

Prolonged Postoperative Paralysis Following Elective Tonsillectomy: A Case of Pseudocholinesterase Deficiency. [PDF]

Cureus
Walsh K, Smith S, Manilla G, Ahluwalia J, Stachler R.   +4 more
europepmc   +1 more source

Growing Together, Thinking Apart: Shared Meaning, Dialectical Thinking, and Family Well‐Being Across Generations

Journal of Adolescence, EarlyView.
ABSTRACT Background Adolescence is a period when families must balance emotional connection with growing autonomy. How family functioning supports well‐being during this transition remains unclear, particularly in cultural contexts that value harmony amid difference.
Tiange Sui, Jerf W. K. Yeung
wiley   +1 more source