Clotrimazole‐loaded PLGA microparticles for local drug delivery to the vagina: Shape does matter
Animal Models and Experimental Medicine, EarlyView.Clotrimazole‐loaded PLGA microparticles for intravaginal delivery. Abstract Background Intravaginal drug administration is the most promising strategy for treating vaginal infections to protect women's health, such as vulvovaginal candidiasis (VVC). However, conventional vaginal formulations in the clinic face challenges such as drug leakage and low ...
Yanyu Li +8 more
wiley +1 more source
Recurrent gastric variceal bleeding due to wandering spleen - complete resolution following laparoscopic splenectomy: A case report. [PDF]
Medicine (Baltimore)Jin BC, Seo SY, Baek HS, Kim SW, Kim SW.
europepmc +1 more source
Natural Aging of Biomaterials in Ambient and Physiological Environments
Advanced NanoBiomed Research, EarlyView.Biomaterials used in biomedical applications can change their physical properties over time, even under ambient and physiological conditions. This review highlights key studies on the natural aging of materials ranging from soft hydrogels to metals and ceramics, emphasizing how time‐dependent changes influence function and performance.
Shuyu Zhang, Anne E. Staples
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Beyond PEGylation: Archaeal Lipids for Long‐Circulating Liposomes
Advanced NanoBiomed Research, EarlyView.Archaeal lipid‐based liposomes, particularly those containing caldarchaeol (GDGT), were found to significantly prolong the circulation time of vancomycin in rats, matching the pharmacokinetic properties of PEGylated systems. These findings suggest archaeal lipids as promising non‐PEG excipients for parenteral applications to minimize drug clearance ...
Viktor Sedlmayr +9 more
wiley +1 more source
Gastric volvulus in an elderly male with a hiatal hernia and a wandering spleen: a case report. [PDF]
J Surg Case RepAlsobyani F +4 more
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Verse, voice, and body:the retirement mode and women's poetry 1680-1723 [PDF]
, 2007 Price, Bronwen
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Tunable Regional Targeting of Self‐Assembling Peptide Nanomaterials in Acute Myocardial Infarction
Advanced NanoBiomed Research, EarlyView.In a rat model of acute myocardial infarction, intravascular delivery of peptide nanofibers with a collagen‐targeting peptide bound to the infarct vasculature while globular peptide nanoparticles penetrated into the infarct area. This study demonstrated that size, shape, and surface chemistry of nanomaterials control the delivery location within the ...
Alexander Chen +14 more
wiley +1 more source
The enigmatic wandering spleen: managing three cases in a tertiary setting. [PDF]
BMC PediatrAl Blooshi M +4 more
europepmc +1 more source
Wandering Spleen After Sleeve Gastrectomy as a Cause of Sigmoid Volvulus. [PDF]
Cureus, 2023 Snyder EN, Rao A, Rehrig ST.
europepmc +1 more source