Effects of disrupting the polyketide synthase gene
BMC Microbiology, 2006 Background Wangiella dermatitidis is a human pathogenic fungus that is an etiologic agent of phaeohyphomycosis. W. dermatitidis produces a black pigment that has been identified as a dihydroxynaphthalene melanin and the production of this pigment is ...
Mandal Piyali +5 more
doaj +2 more sources
Exophiala (Wangiella) dermatitidis and cystic fibrosis – Prevalence and risk factors [PDF]
Medical Mycology, 2010 The objective of this prospective study was to assess the prevalence of Exophiala dermatitidis in respiratory secretions of patients with cystic fibrosis (CF) and to identify risk factors for its presence. The results of all cultures performed over a 2-year period in non lung-transplant patients in our CF clinic were included in the study.
Patrick, Lebecque +6 more
openaire +3 more sources
Exophiala dermatitidis: Key issues of an opportunistic fungal pathogen
Virulence, 2019 The black yeast Exophiala dermatitidis is an opportunistic pathogen, causing phaeohyphomycosis in immunosuppressed patients, chromoblastomycosis and fatal infections of the central nervous system in otherwise healthy Asian patients.
Lisa Kirchhoff +3 more
doaj +2 more sources
72‐year‐old man with right homonymous hemianopia and gait instability
Brain Pathology, Volume 32, Issue 3, May 2022., 2022 An elderly man presented with right homonymous hemianopia and gait instability. He was found to have a left occipital ring enhancing lesion that was resected. Neuropathologic examination demonstrated a Cladophialophora bantiana brain abscess (cerebral phaeohyphomycosis).
Shino Magaki +5 more
wiley +1 more source
Melanins as Sustainable Resources for Advanced Biotechnological Applications
Global Challenges, Volume 5, Issue 2, February 2021., 2021 Melanin‐based materials have broad applicability in materials science and engineering for medical and technical applications. This review offers an overview of the techniques used to analyze their chemical, electrical, optical, and paramagnetic properties with a view to their use as sustainable resources for advanced biotechnological applications that ...
Hanaa A. Galeb +8 more
wiley +1 more source
Cloning and functional characterization of the WdSTUA and WdPACC genes of Wangiella dermatitidis [PDF]
, 2007 To study the function of WdStuAp and WdPacCp in Wangiella dermatitidis, a black, polymorphic fungal pathogen of humans with yeast phase predominance, WdSTUA and WdPACC were cloned, sequenced, disrupted and expressed.
Wang, Qin, 1970 Nov. 15-
core +3 more sources
Characterization of four septin genes, and detection of genetic interactions between WdCDC10 and chitin synthase genes during yeast budding in the polymorphic mold, Wangiella (Exophiala) dermatitidis [PDF]
, 2007 Septins are a highly conserved family of eukaryotic proteins having significant homology within and among species. In the budding yeast, Saccharomyces cerevisiae, a septin-based hierarchy of proteins is required to localize chitin in the bud neck prior ...
Park, Changwon
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Environmental Microbiology, Volume 21, Issue 3, Page 913-927, March 2019., 2019 Summary Perylenequinones are a family of structurally related polyketide fungal toxins with nearly universal toxicity. These photosensitizing compounds absorb light energy which enables them to generate reactive oxygen species that damage host cells.
Malaika K. Ebert +7 more
wiley +1 more source
Disseminated Exophiala dermatitidis causing septic arthritis and osteomyelitis
BMC Infectious Diseases, 2018 Background Exophiala dermatitidis is a melanized fungus isolated from many environmental sources. Infections caused by Exophiala species are typically seen in immunocompromised hosts and manifest most commonly as cutaneous or subcutaneous disease ...
Raynell Lang +3 more
doaj +1 more source
Deregulation of secondary metabolism in a histone deacetylase mutant of Penicillium chrysogenum
MicrobiologyOpen, Volume 7, Issue 5, October 2018., 2018 Deletion of the histone deacetylase gene hdaA of Penicillium chrysogenum induces a pleiotropic effect on secondary metabolism. The hdaA deletion results in the transcriptional activation of the sorbicillinoids biosynthetic gene cluster. Sorbicilloids cause repression of a series of secondary metabolism genes.
Fernando Guzman‐Chavez +7 more
wiley +1 more source