Results 171 to 180 of about 77,846 (258)

Arabic Validation of the Noise-Induced Hearing Loss-Symptoms (NIHL-S) Scale Among Civilians Exposed to Loud Blasts During the 2024 Israeli Invasion of Lebanon. [PDF]

Health Sci Rep
Nasr C, Hallit R, Malaeb D, El Haj M, Sakr F, Dabbous M, El Khatib S, Fekih-Romdhane F, Hallit S, Obeid S.   +9 more
europepmc   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Mental health distress and associated factors among online CBT service users during the Iron Swords War. [PDF]

Front Psychol
Hirsh-Yechezkel G, Zaslavsky-Paltiel I, Farhi A, Edelman-Yaron S, Sarafraz R, Barkai G, Amir H, Porat J.   +7 more
europepmc   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Myoelectric and Progressive Motor Training for Phantom Limb Pain in People with Amputations During War: A Feasibility Report. [PDF]

J Pain Res
Ksenchyna K, Huk Y, Kristoffersen MB, Buist M, McGowan E, Limakatso K, Kovalenko S, Dmytriiev D, Ortiz-Catalan M.   +8 more
europepmc   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Absence of Bacterial Fluorescence Is Associated With Early Response to Skin Substitutes in Diabetic and Venous Ulcers: A Single-Blinded Prospective Study. [PDF]

Int Wound J
Oropallo A, Rao AS, Kaplan S, Baksh F, Isgro J, Iddriss A, Del Pin C.   +6 more
europepmc   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Prioritizing Health in War and Conflict: The 2025 War in Iran and the Call for Global Peace. [PDF]

Int J Health Policy Manag
Raoofi A, Ehsani-Chimeh E, Takian A.
europepmc   +1 more source

AI-WAR: a novel warfarin management software with a bidirectional LSTM dosing model improves time in therapeutic range. [PDF]

Front Pharmacol
Li Y, Xu N, Song L, Liu Y, Pei Q, Kuang Y, Yang G.   +6 more
europepmc   +1 more source