Results 191 to 200 of about 1,545,142 (278)

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Giorgio Mariani, Waging War on War: Peacefighting in American Literature

European Journal of American Studies, 2017
Rachele Dini
doaj   +1 more source

A mediation model on how PTSD symptoms are related to psychotic experiences in survivors of the ongoing Gaza war 2023-2024. [PDF]

Confl Health
Fekih-Romdhane F, Nemr T, Jebreen K, Swaitti T, Jebreen M, Radwan E, Kammoun-Rebai W, Nawajah I, Shamsti O, Obeid S, Hallit S.   +10 more
europepmc   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

Demographic predictors of trauma and depression in war-affected children from Poland and Ukraine: Implications for prevention of mental health problems. [PDF]

Prev Med Rep
Stanisławska-Kubiak M, Wiśniewska-Szeplewicz D, Andrusiewicz M, Katolyk H, Stanisławska M, Malak R, Stelcer B, Czarnecka-Iwańczuk M, Teusz G, Mojs E.   +9 more
europepmc   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

War-related vicarious trauma among healthcare providers in the war-torn tigray, Northern Ethiopia. [PDF]

PLoS One
Hidru HD, Tequare MH, Berhe AK, Kidane GG, Gebre YG, Ebrahim MM, Gebreyesus A, Gebrekidan GB, Mengesha RE, Meles GG, Gebreslassie AA, Abreha BB, Teklemichael DM, Aregawi BG, Gebremedhin HT, Gebretsadik GG, Tesfau YB, Mezgebe GE, Asreshey ZW, Medhin G, Gebretnsae H, Haile YA, Desta TG, Tesfay TB, Gebremariam A.   +24 more
europepmc   +1 more source

War Literature

Istanbul University Faculty of Letters Journal of Turkish Language and Literature, 2018
openaire   +2 more sources

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

FEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel, Nils Hampel, Afshin Iram, Julia Hesse, Constanze Wiek, Jasmin Thuy Vy Nguyen, Helmut Hanenberg, Jürgen Scheller, M. Reza Ahmadian, Björn Stork, Doreen M. Floss, Roland P. Piekorz   +13 more
wiley   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source