Results 211 to 220 of about 2,670,639 (286)

US professional medical societies' public statements regarding violence in Palestine and Israel from October to December 2023: a mixed-methods study. [PDF]

BMJ Open
Conroy C, Bylsma S, Nasari A, Alsamman S, Powers CA, Dhanuka M, Falah N, Akhter S, Asi YM, Wispelwey BP, Mills DM.   +10 more
europepmc   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Mental health of children with epilepsy in Ukraine during the war. [PDF]

Epilepsia
Kharytonov V, Cross JH, Dubenko A, Wiebe S, ILAE Emergency Task Force for Ukraine.   +4 more
europepmc   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Determinants of fertility intentions in a low-fertility region of Central Europe: a cross-sectional survey of 1,092 respondents in the Greater Poland Voivodeship. [PDF]

Front Public Health
Ciborek A, Chęcińska-Maciejewska Z, Nowak A, Krauss H.   +3 more
europepmc   +1 more source

Post-trauma mental health in children and adolescents: phenomenology, aetiology and treatment. [PDF]

Eur J Psychotraumatol
Halligan SL, Meiser-Stedman R.
europepmc   +1 more source

War-Related Posttraumatic Stress Symptoms During the First Two Postpartum Years: The Moderating Role of Childhood Adversity. [PDF]

Stress Health
Chasson M, David A, Shai D, Borelli JL.
europepmc   +1 more source

Associations Between Neurological Diseases and Dioxin Exposure Originating from Agent Orange in Vietnam: A Narrative Review. [PDF]

Toxics
Pham-The T, Nguyet Pham HT, Folk WR, Tran NN, Tran-Thi TH, Nishijo H, Nishijo M.   +6 more
europepmc   +1 more source