Results 61 to 70 of about 45,199 (247)
French thinker Jean Baudrillard, in most of his work, aimed at explaining the nature of capitalism as well as the contribution made by the media for the sake of perpetuity of the system.
İpek Karakoyun
doaj +1 more source
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Women war reporters’ resistance and silence in the face of sexism and sexual violence
Women began reporting on war in the mid-nineteenth century, covering, among other wars, Europeans revolutions and the US Civil War. The numbers of women reporting on war increased over the twentieth century with the First and Second World Wars and ...
Linda Steiner
doaj
From Vietnam to Iraq: Negative trends in television war reporting
In 1876, an American newspaperman with the US 7th Cavalry, Mark Kellogg, declared: ‘I go with Custer, and will be at the death.’ This overtly heroic pronouncement embodies what many still want to believe is the greatest role in journalism: to go up to ...
Tony Maniaty
doaj +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
REVIEW: A revelation about human rights and the ‘war on terror’
Review of The Great War for Civilisation: The Conquest of the Middle East, by Robert Fisk Since 9/11 and the US-led invasion of Afghanistan and Iraq, British journalist Robert Fisk has built a huge following as a staunch critic of George W.
Jon Stephenson
doaj +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source

