Results 11 to 20 of about 159,449 (304)
Autophagy, Warburg, and Warburg Reverse Effects in Human Cancer [PDF]
BioMed Research International, 2014 Autophagy is a highly regulated-cell pathway for degrading long-lived proteins as well as for clearing cytoplasmic organelles. Autophagy is a key contributor to cellular homeostasis and metabolism. Warburg hypothesized that cancer growth is frequently associated with a deviation of a set of energy generation mechanisms to a nonoxidative breakdown of ...
González, Claudio Daniel +5 more
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An Apoptotic and Endosymbiotic Explanation of the Warburg and the Inverse Warburg Hypotheses [PDF]
International Journal of Molecular Sciences, 2018 Otto Warburg, a Nobel prize winner, observed that cancer cells typically “switch” from aerobic to anaerobic respiration. He hypothesized that mitochondrial damage induces neoplastic transformation. In contrast, pathological aging is observed mainly in neuron cells in neurodegenerative diseases.
Szymon Kaczanowski +2 more
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Orphanet Journal of Rare Diseases, 2006 Walker-Warburg Syndrome (WWS) is a rare form of autosomal recessive congenital muscular dystrophy associated with brain and eye abnormalities. WWS has a worldwide distribution. The overall incidence is unknown but a survey in North-eastern Italy has reported an incidence rate of 1.2 per 100,000 live births.
Schachter Harry, Vajsar Jiri
openaire +5 more sources
Dandy-Walker malformation: is the "tail sign" the key sign? [PDF]
, 2015 OBJECTIVE.To demonstrate the value of the "tail sign" in the assessment of Dandy-Walker Malformation (DWM). METHODS: A total of 31fetal MRI, performed before 24 weeks of gestation after second-line US examination between May 2013 and September 2014 ...
Aliberti, C +10 more
core +1 more source
Art history and empiricism: a response to Ian Verstegen’s review of Meyer Schapiro’s Critical Debates [PDF]
Journal of Art Historiography, 2022 In this letter to the editor, I counter Ian Verstegen’s suggestion in his recent review of my book that Meyer Schapiro’s critiques of the grand theories of the 20th century were anti-theoretical. Rather than sceptical refutations of art-historical theory
C. Oliver O’Donnell
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The Warburg Dance Movement Library-The WADAMO Library: A Validation Study [PDF]
, 2019 The Warburg Dance Movement Library is a validated set of 234 video clips of dance movements for empirical research in the fields of cognitive science and neuroscience of action perception, affect perception and neuroaesthetics.
Christensen, J. F. +2 more
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Nature Communications, 2021 X-chromosome inactivation (XCI) ensures dosage compensation between the sexes. Here the authors perform allele-specific single-cell RNA sequencing in differentiating mouse embryonic stem cells to provide a detailed profile of the onset of XCI.
Guido Pacini +6 more
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Is Lactate an Oncometabolite? Evidence Supporting a Role for Lactate in the Regulation of Transcriptional Activity of Cancer-Related Genes in MCF7 Breast Cancer Cells. [PDF]
, 2019 Lactate is a ubiquitous molecule in cancer. In this exploratory study, our aim was to test the hypothesis that lactate could function as an oncometabolite by evaluating whether lactate exposure modifies the expression of oncogenes, or genes encoding ...
Brooks, George A +4 more
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Phospho‐tyrosine dependent protein–protein interaction network
Molecular Systems Biology, 2015 Post‐translational protein modifications, such as tyrosine phosphorylation, regulate protein–protein interactions (PPIs) critical for signal processing and cellular phenotypes.
Arndt Grossmann +6 more
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Molecular Systems Biology, 2022 Protein kinases play an important role in cellular signaling pathways and their dysregulation leads to multiple diseases, making kinases prime drug targets.
Stefanie Jehle +6 more
doaj +1 more source