Results 131 to 140 of about 6,205 (262)

Solution of supply chain management problems using rough t spherical fuzzy set lower and upper approximation spaces. [PDF]

Sci Rep
Zhao X, Zhou Y, Sun L.
europepmc   +1 more source

A Metabolic‐Epigenetic Axis of AARS1/IGF2BP3‐K280 Lactylation Sustains Endometrial Cancer Stemness and Recurrence

Advanced Science, EarlyView.
Lactate‐driven endometrial cancer relapse is mediated by enzymatic protein modification. Elevated lactate levels activate AARS1, which catalyzes K280 lactylation of IGF2BP3, therefore stabilizing HMGA2 mRNA and promoting tumor stemness and recurrence.
Peng Jiang, Yunfeng Zheng, Chenfan Tian, Yuan Tu, Xiaoxia Chang, Jiaxin Yu, Hangkun Yu, Chunxia Gong, Jie Xiong, Philip N. Baker, Yong Fu, Chao Tong   +11 more
wiley   +1 more source

Prevalence of night work in the Brazilian employed population. [PDF]

Rev Bras Med Trab
Dos Santos Júnior CJ, Fischer FM.
europepmc   +1 more source

An Extracellular Pore‑Targeting Peptide Defines a Designable Allosteric Site in TRPV2

Advanced Science, EarlyView.
Structure‐guided peptide engineering yields Depiv2, a highly potent and subtype‐selective TRPV2 inhibitor that binds to the extracellular pore and remodels it into a closed, non‐conductive state. Depiv2 suppresses pathological cardiac hypertrophy, establishing the TRPV2 outer pore as a designable interface for selective peptide modulation.
Aiqin Zhu, Hongkun Wang, Jiawei Wang, Xiaolu Liu, Aerziguli Aierken, Lizhen Xu, Ping Liang, Fan Yang   +7 more
wiley   +1 more source

The development and use of data warehousing in clinical settings: a scoping review. [PDF]

Front Digit Health
Lyu S, Craig S, O'Reilly G, Taniar D.
europepmc   +1 more source

High‐Temperature Magnetic Field Mapping Using a Single‐Crystal Diamond MEMS Resonator Array

Advanced Science, EarlyView.
A single‐crystal diamond MEMS resonator array enables magnetic‐field reconstruction with millisecond response, nanotesla level magnetic noise, and stable operation up to 573 K. Two‐ and three‐dimensional magnetic field mapping are demonstrated using ΔEeffect sensing, highlighting the potential of diamond MEMS technology for hightemperature magnetic ...
Zilong Zhang, Keyun Gu, Satoshi Koizumi, Masaya Toda, Meiyong Liao   +4 more
wiley   +1 more source

Optimizing circular industrial integration for sustainable yarn production with remanufacturing: a carbon policy-based modelling approach. [PDF]

Sci Rep
Sahadevan VK, Thomas A, Mishra U.
europepmc   +1 more source

Longitudinal Awake Mouse Brain Imaging Using Functional Ultrasound and Functional Ultrasound Localization Microscopy

Advanced Science, EarlyView.
Awake longitudinal multimodal ultrasound imaging integrates functional ultrasound (fUS), ultrasound localization microscopy (ULM), and functional ULM (fULM) to characterize cerebrovascular function, microvascular architecture, and flow dynamics within the same animals over time.
Zhe Huang, Yike Wang, Matthew R. Lowerison, Yue Xu, Murong Yi, Bing‐Ze Lin, YiRang Shin, Nathiya Vaithiyalingam Chandra Sekaran, Daniel A. Llano, Pengfei Song   +9 more
wiley   +1 more source

SC-DGLA: constraint-aware pallet demand forecasting with dynamic graph and learnable lag alignment. [PDF]

Sci Rep
Ye B, Zheng J, Zhu L, Chen Y, Lei X, Zhang B, Wang Y.   +6 more
europepmc   +1 more source

LAPTM5 Downregulation‐Driven VAMP8 Phosphorylation Impairs Autophagosome‐Lysosome Fusion and Aggravates Septic Acute Lung Injury

Advanced Science, EarlyView.
LAPTM5 functions as a critical molecular scaffold bridging PGAM5 and VAMP to facilitate PGAM5‐mediated dephosphorylation of VAMP8. This cascade promotes autophagosome‐lysosome fusion, restores impaired autophagic flux, and clears damaged mitochondria, thereby mitigating cellular oxidative stress and systemic inflammation.
Lang Jiang, Qilan Li, Hao Liu, Xuehui Gao, Hongyu Nie, Lang Chen, Mei He, Xuefeng Li, Xiangming Fang, Jiqian Xu, Hao Zhang, Jiahong Xia, You Shang   +12 more
wiley   +1 more source