Results 221 to 230 of about 1,051,364 (309)

Identification and classification method of landslide pattern in the soil water index-based early warning system. [PDF]

Sci Rep
Zhu Y, Wang B, Zhang Y, Sun Z.
europepmc   +1 more source

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

Advanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong, Yuhang Xie, Zhijie Weng, Yongzhi Wu, Longjiang Li, Bo Li   +5 more
wiley   +1 more source

A deep learning-based early warning system for renal replacement therapy in the intensive care unit

Mamandipoor B, McAuley J, Krause M, Schmidt U, Hsu C, Gabriel RA.   +5 more
europepmc   +1 more source

A smart automatic control and monitoring system for environmental control in poultry houses integrated with earlier warning system. [PDF]

Sci Rep
Elwakeel AE.
europepmc   +1 more source

Functional Analysis of Ligand‐Gated Chloride Channels in a Cnidarian Sheds Light on the Evolution of Inhibitory Signaling

Advanced Science, EarlyView.
We uncover a large variety of putative inhibitory ligand‐gated ion channels (LGICs) in the phylum Cnidaria, the sister group to all bilaterian animals. Phylogenetic analysis suggests a complex evolutionary history of inhibitory LGICs with diverse neurotransmitter ligands.
Abhilasha Ojha, Linda Kloss, Juan D. Montenegro, Simone Albani, Audrey Ortega‐Ramírez, Mihaela Raycheva, Sylvia Joussen, Sabrina Kaul, Michèle Bachmann, Lisa Huf, Günther Schmalzing, Alison G. Cole, Ulrich Technau, Stefan Gründer   +13 more
wiley   +1 more source

A New Early Warning System for Predicting Adverse Outcomes in Hospitalized Patients With Neurological Conditions: A Retrospective Cohort Study. [PDF]

Cureus
Arellano González C, Niembro Muñoz LE, Aguilar-Lugo-Gerez JJ, Sanchez Závala J.   +3 more
europepmc   +1 more source

De Novo Multi‐Mechanism Antimicrobial Peptide Design via Multimodal Deep Learning

Advanced Science, EarlyView.
Current AI‐driven peptide discovery often overlooks complex structural data. This study presents M3‐CAD, a generative pipeline that leverages 3D voxel coloring and a massive database of over 12 000 peptides to capture nuanced physicochemical contexts.
Xiaojuan Li, Haifan Gong, Yue Wang, Yinuo Zhao, Lixiang Li, Peijing Bao, Qingzhou Kong, Jialu Fu, Boyao Wan, Yumeng Zhang, Jinghui Zhang, Jiekun Ni, Zhongxue Han, Xueping Nan, Kunping Ju, Longfei Sun, Yuerui Ma, Huijun Chang, Mengqi Zheng, Yanbo Yu, Xiaoyun Yang, Xiuli Zuo, Haina Wang, Yanqing Li   +23 more
wiley   +1 more source

Modified National Early Warning Score 2, warning system for predicting treatment outcomes in patients with emphysematous pyelonephritis. [PDF]

World J Nephrol
Al-Haggar MS, Abdelmoneim ZA.
europepmc   +1 more source

High‐Fidelity Synthetic Data Replicates Clinical Prediction Performance in a Million‐Patient Diabetes Cohort

Advanced Science, EarlyView.
This study generates high‐fidelity synthetic longitudinal records for a million‐patient diabetes cohort, successfully replicating clinical predictive performance. However, deeper analysis reveals algorithmic biases and trajectory inconsistencies that escape standard quality metrics. These findings challenge current validation norms, demonstrating why a
Francisco Ortuño, Víctor M. de la Oliva Roque, Javier‐Ignacio Ramirez‐Lopez, David P. Kreil, Joaquín Dopazo, Carlos Loucera   +5 more
wiley   +1 more source

Updating Health Canada's Heat-Health Messages for the Environment and Climate Change Canada Heat Warning System: A Collaboration with Canadian Experts. [PDF]

Int J Environ Res Public Health
Tetzlaff EJ, MacDonald M, Kenny GP, Murphy B, Siblock RF, Al-Hertani A, Stranberg RC, Berry P, Gorman M.   +8 more
europepmc   +1 more source