Results 31 to 40 of about 39,261 (244)
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Time-Dependence of Stop Marks in Warp-Knitted Fabrics
Tekstilec, 2022 Stop marks are one of the most frequently occurring errors in warp-knitted fabrics. They become visible in a fabric each time a warp-knitting machine stops and restarts.
Christian Hellert +2 more
doaj +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Artificial molecular machines and motors—Design and control of nanoscale motion
FEBS Letters, EarlyView.Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Analyzing Warp Drive Spacetimes with Warp Factory [PDF]
The field of warp research has been dominated by analytical methods to investigate potential solutions. However, these approaches often favor simple metric forms that facilitate analysis but ultimately limit the range of exploration of novel solutions ...
Helmerich, Christopher +5 more
core +1 more source
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Realization of an Automated Vertical Warp Stop Motion Positioning
Actuators, 2015 The tension in the warp yarns is a critical variable in the weaving process. If the warp tension is too high or too low the weaving process will be interrupted. A parameter that directly affects the warp tension is the vertical warp stop motion position.
Frederik Cloppenburg +2 more
doaj +1 more source
Research on Computer Simulation of the Stitch Forming Jacquard Warp-Knitted Fabric
, 2019 This paper first briefly introduces the application of computer simulation technology for fabrics and the improvement of loop jacquard warp knitted fabric, then elaborates the importance of the studies, introduces the associated research and improvement ...
Farzana Akter +7 more
core +1 more source
RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells
FEBS Open Bio, EarlyView.RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour +2 more
wiley +1 more source