Results 231 to 240 of about 133,597 (317)

Cortical Effects of Dopamine Replacement Account for Clinical Response Variability in Parkinson's Disease

open access: yesMovement Disorders, EarlyView.
Abstract Background Individual variability in clinical response to dopamine replacement therapy (DRT) is a key barrier to efficacious treatment for patients with Parkinson's disease (PD). A better understanding of the neurobiological sources of such interindividual differences is necessary to personalize DRT prescribing, inform future clinical ...
Alex I. Wiesman   +5 more
wiley   +1 more source

A Convergent Pathway for Stimulation‐Induced Dyskinesia Following Deep Brain Stimulation

open access: yesMovement Disorders, EarlyView.
Abstract Background Stimulation‐induced dyskinesias (SID) from deep brain stimulation (DBS) of the subthalamic nucleus (STN) and globus pallidus internus (GPi) are uncommon; however, they are increasingly recognized. Once considered transient and indicative of effective neuromodulation, SID are now seen as potential therapy‐limiting side effects, akin ...
Joshua K. Wong   +4 more
wiley   +1 more source

Myelin water and tensor‐valued diffusion imaging: (How) are they related?

open access: yesMagnetic Resonance in Medicine, EarlyView.
Abstract Purpose Conventional MRI offers limited insight into specific characteristics of central nervous system tissue, whereas quantitative MRI measures can provide more detailed information about different aspects of microstructure. A multi‐metric approach involving multiple quantitative measures may improve our understanding of healthy tissue and ...
Sharada Balaji   +11 more
wiley   +1 more source

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