Results 181 to 190 of about 413,982 (284)

Structural investigation of human U6 snRNA recognition by spliceosomal recycling factor SART3 RNA recognition motifs

The FEBS Journal, EarlyView.
Human SART3 has two RRM domains to engage with U6 snRNA for spliceosome recycling. This study reports solution structures of SART3 RRM domains and investigates the interaction between RRM and U6 snRNA. SART3 binds to the asymmetric bulge of U6 snRNA as a dimer via conserved positively charged surfaces.
Iktae Kim, Kyeong‐Mi Bang, So Young An, Changkon Park, Ji‐Yeon Shin, Youngim Kim, Hyun Kyu Song, Jeong‐Yong Suh, Nak‐Kyoon Kim   +8 more
wiley   +1 more source

Selenium Content of the Gonads of the Domestic Dog (<i>Canis lupus f. familiaris</i>) in Relation to Sex, Age, and Reproductive Disorders. [PDF]

Animals (Basel)
Skibniewska E, Kołnierzak M, Skibniewski B, Lasocka I, Skibniewski M.   +4 more
europepmc   +1 more source

Zebrafish as a model for Catel–Manzke syndrome—identification and characterization of the zebrafish TGDS ortholog

The FEBS Journal, EarlyView.
Zebrafish Tgds, when expressed as a recombinant protein, catalyzes the dehydration of UDP‐D‐glucose, the initial step in the formation of 6‐deoxyhexoses. Corresponding Tgds mutations found in Catel–Manzke syndrome patients lead to reduced enzymatic activity and stability.
Maria Rosaria Coppola, Deianira Bellitto, Erfan Asgari, Virginia Bazzurro, Giorgia Casucci, Francesco Piacente, Matteo Bozzo, Davide Ceresa, Costantino Parisi, Cecilia Winata, Simona Candiani, Michela Tonetti   +11 more
wiley   +1 more source

Double inlet left ventricle in a 12-year-old European bison: a case report with anatomical assessment and postmortem computed tomography evaluation. [PDF]

BMC Vet Res
Godlewska A, Barszcz K, Przespolewska H, Bielecki W, Zabiega K, Buczyński M, Mądry W, Szymczak K, Kwiatkowska M, Grzegorczyk M, Szaluś-Jordanow O.   +10 more
europepmc   +1 more source

Contrasting Approaches in the Implementation of GRADE Methodology in Guidelines for Haemophilia and Von Willebrand Disease

Haemophilia, EarlyView.
ABSTRACT Introduction The 2024 ISTH clinical practice guideline (CPG) for treatment of congenital haemophilia, the NBDF‐McMaster Guideline on Care Models for Haemophilia Management, and ASH ISTH NBDF WFH guidelines on the diagnosis and management of VWD all utilised GRADE methodology.
Mark W. Skinner, Manuela Albisetti, Jesús Ardila, Jan Astermark, Jan Blatny, Manuel Carcao, Pratima Chowdary, Nathan T. Connell, Miguel Crato, Yesim Dargaud, Roseline d'Oiron, Amy L. Dunn, Miguel A. Escobar, Carmen Escuriola‐Ettingshausen, Emna Gouider, Annie Harroche, Cedric Hermans, Victor Jimenez‐Yuste, Radoslaw Kaczmarek, Gili Kenet, Liane Khoo, Robert Klamroth, Florian Langer, David Lillicrap, Johnny Mahlangu, Christoph Male, Tadashi Matsushita, Sandrine Meunier, Wolfgang Miesbach, Beatrice Nolan, Johannes Oldenburg, Brian O'Mahony, Margareth Ozelo, Glenn F. Pierce, Gloria Ramos, Michael Recht, Olivia Romero‐Lux, Dawn Rotellini, Rita C. Santoro, Tammuella C. Singleton, Alok Srivastava, Sophie Susen, Kate Talks, Huyen Tran, Leonard A. Valentino, Jerzy Windyga, Renchi Yang, Maria Elisa Mancuso, also on behalf of AICE, AHAD‐AP, AHCDC, ATHN, CLAHT, EHC, French CRH & MHEMO, HTCCNC, NBDF, PEDNET, UKHCDO, WFH   +59 more
wiley   +1 more source

Hair Silicon as a Long-Term Mineral Exposure Marker in Coronary Artery Disease: A Pilot Study. [PDF]

Nutrients
Dziedzic EA, Dudek Ł, Osiecki A, Gąsior JS, Kochman W.   +4 more
europepmc   +1 more source

A Conversation With David Bellhouse

International Statistical Review, EarlyView.
Summary David Richard Bellhouse was born in Winnipeg, Manitoba, on 19 July 1948. He studied actuarial mathematics and statistics at the University of Manitoba (BA, 1970; MA, 1972) and completed his PhD at the University of Waterloo, Ontario, in 1975. After being an Assistant Professor for 1 year at his alma mater, he joined the University of Western ...
Christian Genest
wiley   +1 more source

Successful invasive treatment of stroke in a patient with a left ventricle assist device - case report. [PDF]

Postep Psychiatr Neurol
Konopka A, Sienkiewicz-Jarosz H, Ułamek-Kozioł M, Misztal-Ogonowska M, Smaga E, Michałowska I.   +5 more
europepmc   +1 more source

Shame in Response to Institutional Failure

Journal of Applied Philosophy, EarlyView.
ABSTRACT When an institution morally fails, what is the appropriate emotional reaction for those institution members who are causally uninvolved in bringing about this failure? Our aim in this article is to explain why it may be fitting for such people to feel ashamed about the wrongs perpetrated by the institution. We begin by explaining the main case
Alfred Archer, Benjamin Matheson
wiley   +1 more source