Results 131 to 140 of about 1,848,681 (330)

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Nude woman washing face

, 2021
Unknown
openalex   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

The Options for UK Domestic Water Reduction: A Review [PDF]

, 2005
Demand pressure on UK water supplies is expected to increase in the next 20 years driven by increasing population, new housing development and reducing household size. Regionally and locally migration will also afect demand particularly in the South-East.
McDonald, A., Parsons, J., Rees, P., Sim, P.   +3 more
core  

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Escape from washing out of baryon number in a two-zero-texture general Zee model compatible with the large mixing angle MSW solution

, 2003
We propose a two-zero-texture general Zee model, compatible with the large mixing angle Mikheyev-Smirnov-Wolfenstein solution. The washing out of the baryon number does not occur in this model for an adequate parameter range.
A. Zee, A. Zee, A. Zee, A.G. Cohen, A.Y. Smirnov, B.R. Desai, C. Jarlskog, C. S. Lim, C.E. Aalseth, D. Fargion, D.E. Groom, E. Ma, G. Bhattacharyya, G.C. Branco, H.V. Klapdor-Kleingrothaus, J. Schechter, J. Schechter, J.N. Bahcall, J.N. Bahcall, J.T. Peltoniemi, J.T. Peltoniemi, K. Eguchi, K. Hasegawa, K. Ogure, K.R.S. Balaji, K.S. Babu, L. Wolfenstein, L. Wolfenstein, M. Apollonio, M. Apollonio, M. Maltoni, M.C. Gonzalez-Garcia, N. Fornengo, N. Haba, P. Roy, P.H. Frampton, P.H. Frampton, P.H. Frampton, P.H. Frampton, Q.R. Ahmad, R.N. Mohapatra, S. Fukuda, S.T. Petcov, T. Hambye, T. Kitabayashi, T. Kitabayashi, T.J. Weiler, U. Sarkar, V. Barger, V.A. Kuzmin, Y. Fukuda, Y. Fukuda, Y. Fukuda, Y. Koide, Z. Fodor, Z.Z. Xing, Z.Z. Xing, Ø. Elgarøand   +57 more
core   +1 more source

Relationship Analysis between Company Standard, SNI, and International Standard in Washing Machine: A Case Study at an Electronic Company [PDF]

, 2019
Arfan Bakhtiar, Yusuf Widharto, Dyah Ika Rinawati, Maulida Nurfajrianti   +3 more
openalex   +1 more source

Bioremediation of arsenic-contaminated soil through soil washing using biosurfactants

, 2021
Ricardo Silva Coelho, Mônica Cristina Teixeira   +1 more
openalex   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Durable antistatic coating for polymethylmethacrylate [PDF]

, 1977
A durable antistatic coating is achieved on polymethylmethacrylate plastic without affecting its optical clarity by applying to the surface of the plastic a low molecular weight solvent having a high electron affinity and a high dipole moment, such as ...
Hadek, V., Rembaum, A., Somoano, R. B.
core   +1 more source