Results 21 to 30 of about 24,010 (288)
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
New trends in international investment law treaty practice: where does Latin America stand?
Sequência: Estudos Juridicos e Politicos, 2018 Latin-American countries’ attitude towards international investment law hasundergone an evolution. During the 90s, those countries stipulated many BilateralInvestment Treaties (BITs), subscribed to the Washington Convention, and, recently,they have been ...
Mara Valenti
doaj +1 more source
Disability prevalence: comparing four types of disability measures in the community
Bulletin of Faculty of Physical Therapy, 2023 Background There is no general consensus on how to measure disability and disability prevalence rates. The results of previous estimates could not be compared due to the varied nature of the methodologies used and the lack of standardization in the ...
G. Shankar Ganesh +4 more
doaj +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Book Review. Women After All: Sex, Evolution, and the End of Male Supremacy
Humaniora, 2016 Konner’s Women After All begins with thequotation from Elizabeth Cady Stanton, a leading figure of the American suffragist, “Because man and woman are the complement of one another, we need woman’s thought in national affairs to make a safe and stable ...
Mala Hernawati
doaj +1 more source
Leaf Endophytes of Populus trichocarpa Act as Pathogens of Neighboring Plant Species
Frontiers in Microbiology, 2020 The conventional definition of endophytes is that they do not cause disease, whereas pathogens do. Complicating this convention, however, is the poorly explored phenomenon that some microbes are endophytes in some plants but pathogens in others.
George Newcombe +3 more
doaj +1 more source
MiR‐513a promotes human erythroid differentiation by modulating c‐Jun
FEBS Open Bio, EarlyView.During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim +11 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Introduction Spinal cord infarction (SCI) is a rare but devastating myelopathy, characterized by a high disability rate and an unfavorable prognosis. It has often been underdiagnosed and misdiagnosed as idiopathic transverse myelitis (ITM). This study aimed to describe the clinical features, radiological biomarkers, treatments, and functional ...
Zeqiang Ji +13 more
wiley +1 more source
The Northern Sea Route: Problems of National Status Legitimization under International Law. Part I
Арктика и Север, 2020 The Northern Sea Route (NSR) for the Russian Federation is a strategically important maritime communication with the status of a historically established national transport artery.
Pavel A. GUDEV
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Ecosphere, 2022 Wildlife managers tasked with understanding habitat and resource selection at the population level attempt to characterize patterns in nature that aid and inform conservation. Resource selection functions (RSFs), such as discrete choice analyses, are the
Emily D. Thorne, W. Mark Ford
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