Results 201 to 210 of about 99,429 (347)

Equine botulism

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Botulism is a severe and often fatal disease in equine patients worldwide. Clostridium botulinum is a ubiquitous soil organism which produces a potent neurotoxin resulting in neuromuscular blockade and flaccid paralysis in affected animals. Definitive diagnosis is often impractical or impossible, leading to diagnosis and treatment based on ...
Kali Slavik   +2 more
wiley   +1 more source

Structural and functional dissection of the WH2/DAD motif of INF2, a formin linked to human inherited degenerative disorders

open access: yesThe FEBS Journal, EarlyView.
The INF2 WH2/DAD domain, composed of hydrophobic and basic regions, forms a single α‐helix in solution. The hydrophobic segment is essential for INF2 function, as its deletion disrupts actin dynamics and causes nuclear abnormalities, like those seen in pathogenic INF2 DID variants. In contrast, natural INF2 WH2/DAD variants found in patients with renal
Leticia Labat‐de‐Hoz   +5 more
wiley   +1 more source

Toward a global repository of insect traits (GRIT)

open access: yesInsect Conservation and Diversity, EarlyView.
Biodiversity loss is accelerating, yet insect conservation is hindered by the absence of a centralised, comprehensive trait database. We propose the GRIT, a FAIR, open‐access platform uniting datasets and collaborators worldwide. GRIT will harness advanced computational tools for trait acquisition and imputation, enabling large‐scale ecological ...
Pedro Cardoso   +37 more
wiley   +1 more source

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