Results 221 to 230 of about 40,338 (304)

A phase 1 study of berzosertib (M6620, VX‐970) in combination with cisplatin and radiation in patients with locally advanced head and neck squamous cell carcinoma (ETCTN 9950)

open access: yesCancer, Volume 132, Issue 6, 15 March 2026.
ABSTRACT Background Ataxia telangiectasia Rad3‐related (ATR) protein kinase regulates DNA damage response and is essential for tumor cell survival. Preclinically, ATR inhibition can sensitize tumor cells to radiation and chemotherapy. The authors conducted a phase 1 trial of berzosertib, a selective ATR inhibitor, in combination with definitive ...
Aarti Bhatia   +26 more
wiley   +1 more source

Flies use acetic acid to protect their offspring from parasitoids. [PDF]

open access: yesPLoS Pathog
Reddy KF   +3 more
europepmc   +1 more source

Low YTHDC1 Expression Upregulates FSCN1 to Promote Nuclear F‐Actin Formation and Facilitate Double‐strand DNA Breaks Repair in TMZ‐Resistant Glioblastoma

open access: yesAdvanced Science, Volume 13, Issue 13, 3 March 2026.
This study revealed that low expression of YTHDC1 in TMZ‐resistant GBM cells leads to increased FSCN1 expression, which is suppressed by m6A modification. FSCN1 activates the CDC42/N‐WASP/Arp2/3 axis in the cell nucleus by recruiting the guanine nucleotide exchange factor (GEF) family member FGD1, thereby promoting F‐actin polymerization in the nucleus.
Minglong Yang   +9 more
wiley   +1 more source

Potential for the American toad (Anaxyrus americanus) to contribute to biological control in a vegetable agroecosystem

open access: yesAgrosystems, Geosciences &Environment, Volume 9, Issue 1, March 2026.
Abstract The American toad (Anaxyrus americanus) is a native insectivorous amphibian common in agricultural fields in eastern North America. Past research on this and related species suggests potential for positive or negative effects on pest populations, depending on the prevalence of intraguild predation.
Margaret R. Douglas   +6 more
wiley   +1 more source

Large-scale Genome Analyses Provide Insights into Hymenoptera Evolution. [PDF]

open access: yesMol Biol Evol
He C   +17 more
europepmc   +1 more source

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