Results 191 to 200 of about 488,219 (300)

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

Advanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong, Yuhang Xie, Zhijie Weng, Yongzhi Wu, Longjiang Li, Bo Li   +5 more
wiley   +1 more source

Selective electrochemical oxidation of biomass and waste plastic at higher current densities for simultaneous hydrogen generation through hybrid water electrolysis. [PDF]

Chem Sci
Behera S, Negi A, Joshi G, Chauhan C, Kanthali DS, Khatua S, Mondal B.   +6 more
europepmc   +1 more source

Analysis of the Influence of Production Method, Plastic Content on the Basic Performance of Waste Plastic Modified Asphalt. [PDF]

Polymers (Basel), 2022
Li H, Zhou L, Sun J, Wang S, Zhang M, Hu Y, Temitope AA.   +6 more
europepmc   +1 more source

Discovery of an Adaptive Neuroimmune Response Driving Itch and Fast Tick Removal with Implications for Preventing Pathogen Transmission

Advanced Science, EarlyView.
Itch‐induced tick removal (IITR): An acquired neuroimmune mechanism, itch‐induced tick removal, develops after repeated tick exposure, mobilizing T cells and macrophages at the tick bite site to trigger a rapid scratching response that facilitates timely tick removal within a critical window that precedes the transmission of many tick‐borne pathogens ...
Johannes S. P. Doehl, Tiago D. Serafim, Serena Doh, Charles S. Grugan, Eva Iniguez, Luana Rogerio, Ronja Frigard, Ranadhir Dey, Pedro Cecilio, Xinglong Gu, Pang‐Yen Tseng, Aline da Silva Moreira, Mahnaz Minai, James Oristian, Hans Ackerman, Steven Brooks, Caroline Percopo, Siu‐Ping Ng, Derron A. Alves, Lucas Tirloni, Jennifer M. Anderson, Adriana Marques, Fabiano Oliveira, Shaden Kamhawi, Daniel E. Sonenshine, José M. C. Ribeiro, Mark Hoon, Jesus G. Valenzuela   +27 more
wiley   +1 more source

Recent Advances on Thermochemical Recycling of End-of-Life Tires and Their Coblending with Waste Plastic Fractions. [PDF]

ACS Omega
Yaghi A, Ali L, Altarawneh M.
europepmc   +1 more source

Catalytic Copyrolysis of Used Waste Plastic and Lubricating Oil Using Cu-Modification of a Spent Fluid Catalytic Cracking Catalyst for Diesel-like Fuel Production. [PDF]

ACS Omega, 2023
Charusiri W, Phowan N, Permpoonwiwat A, Vitidsant T.   +3 more
europepmc   +1 more source

Delivery of Pleckstrin‐Homology Domains Suppresses PI3K/Akt Signaling and Breast Cancer Metastasis

Advanced Science, EarlyView.
Current therapies curb tumor growth but not metastasis. Obscurin, a giant metastasis suppressor lost in breast cancer, restrains PI3K/Akt signaling but is impractical to restore. We deploy a mini‐obscurin, comprising the obscurin‐PH‐domain, which sequesters PI3K‐p85, potently suppressing invasion and metastasis.
Matthew Eason, Anindya Sen, Suhan Cho, Se Jong Lee, Keyata Thompson, Md Musavvir Mahmud, Poornima Dubey, Talia Guardia, Anthony Kim, Stuart Martin, Nathan Wright, Konstantinos Konstantopoulos, Aikaterini Kontrogianni‐Konstantopoulos   +12 more
wiley   +1 more source

Hybrid deep learning and RSM modeling of diesel engine performance using TiO₂ doped butanol and waste plastic oil blends. [PDF]

Sci Rep
Sunil Kumar K, Ali ABM, Razak A, Anqi AE, Rajhi AA, Emma AF, Khan MA.   +6 more
europepmc   +1 more source

Storage stability performance of composite modified asphalt with scrap non-tire automotive rubber, waste plastic pyrolytic oil and sulfur. [PDF]

PLoS One, 2023
Kumar A, Choudhary R, Kumar A.
europepmc   +1 more source

Lymphoid‐Tissue‐on‐Chip Recapitulates Human Antibody Responses In Vitro

Advanced Science, EarlyView.
The presented lymphoid‐tissue‐on‐chip system allows culture of primary human tonsil cells at organotypic high density under perfusion for up to 4 weeks, emulates immune response to soluble vaccines and vaccination via peripheral antigen‐presenting cells and represents a useful tool to assess cellular interactions during homeostasis, immune responses ...
Claudia Teufel, Anna‐Sophie Schlemmer, Andrea W. Eiken, Zachary W. Wagoner, Dennis Vöhringer, Lena Christ, Alex Dulovic, Patrick Marsall, Madeleine Fandrich, Eduardo J. S. Brás, Julia Marzi, Friederike Bärhold, Julia Philipp, Sven Becker, Lisa E. Wagar, Peter Loskill   +15 more
wiley   +1 more source