Results 41 to 50 of about 346,997 (316)

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

The Off Gas Treatment In The Process Of Vitrification And Incineration of Nuclear Waste [PDF]

open access: yes, 2012
The off gas treatment in the process of vitrification and incineration of nuclear waste has been studied for the purpose of the effectiveness treatment system evaluation and using its equipment. The off gas from vitrification process leaves the melter at
Herlan , Martono, A, Aisyah
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Treatment of piggery wastes in waste stabilization ponds

open access: yesWater Science and Technology, 2002
The piggery industry produces high effluent loads. This is due to the high concentration of animals kept in a confined space, foods with high protein content that are not well assimilated by the animals, and poor on-farm water management. In this study, we present the characteristics, design, site selection, soil study, and the construction of a pilot ...
V E E, Estrada, D E A, Hernández
openaire   +2 more sources

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

open access: yesFEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa   +2 more
wiley   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

open access: yesFEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik   +6 more
wiley   +1 more source

Hazardous Wastes Treatment Technologies [PDF]

open access: yesWater Environment Research, 2018
A review of the literature published in 2017 on topics relating to hazardous waste management in water, soils and air. This review covers hazardous waste treatment theologies and applying physical, chemical, and biological principles.
Jianmin, Wang   +4 more
openaire   +2 more sources

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

Melting and draining tests on glass waste form for the immobilization of Cs, Sr, and rare-earth nuclides using a cold-crucible induction melting system

open access: yesNuclear Engineering and Technology, 2022
Cold-crucible induction melting (CCIM) technology has been intensively studied as an advanced vitrification process for the immobilization of highly radioactive waste.
Jung-Hoon Choi   +5 more
doaj   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi   +2 more
wiley   +1 more source

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