Results 41 to 50 of about 230,025 (252)

Chemical reactions and conditions of mineral formation at tailings storage facilities of the Russian Far East

open access: yesГорные науки и технологии, 2021
Cassiterite-sulfide and polymetallic deposits of the Far Eastern Region (FER) were mined by both openpit and underground methods. This resulted in the emerging numerous mine workings and tailings storage facilities (TSFs) (abandoned without reclamation ...
V. P. Zvereva   +2 more
doaj   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

open access: yesFEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana   +3 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Smart biofilms produced from fish filleting wastes [PDF]

open access: yes, 2017
The myofibrillar proteins utilization from fish processing wastes to produce films has an importance to decrease the environmental impact due to usual inappropriate disposal of these wastes.
Pino Hernández, Enrique   +9 more
core   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani   +9 more
wiley   +1 more source

Handling and Storage of Hazardous wastes [PDF]

open access: yes, 2008
Hazardous wastes are likely to include asbestos, batteries, gas canisters, hospital wastes, industrial wastes, oils, chemical wastes, pesticides, fungicides, etc.
Meekings, Helen, Bjerregaard, Martin
core  

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

open access: yesMolecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David   +12 more
wiley   +1 more source

Composition and distribution of organic waste in Ireland : implications for land application practices [PDF]

open access: yes, 2008
Paper presented at Agricultural and biosystems engineering for a sustainable world. International Conference on Agricultural Engineering, Hersonissos, Crete, Greece, 23-25 June, 2008Questions about the economic and environmental sustainability of current
Taffese Tanto, Mebrate, Magette, W. L.
core   +1 more source

Defense and Protection of the Marine Coastal Areas and Human Health: A Case Study of Asbestos Cement Contamination (Italy)

open access: yesGeosciences
Pivotal environmental geology research was carried out in the protected area of Cape Peloro (Messina, NE Sicily, Italy). The main aims were the ascertainment of the presence of Asbestos Cement Materials (ACMs), their mapping, and, consequently, an ...
Roberta Somma   +7 more
doaj   +1 more source

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