Results 181 to 190 of about 12,493,917 (291)

A multivariate dataset on water-energy-food nexus: Multi-actor governance for social justice. [PDF]

Data Brief
Saul N, Marjanneke J V, Willemien D, Leocadia Z, Germarié V, Patrick N, Tiisetso J R, Naziha M, Bronwen Q, Sibulele B, Alois A M.   +10 more
europepmc   +1 more source

Coupling and Coordination Degrees of the Core Water⁻Energy⁻Food Nexus in China. [PDF]

Int J Environ Res Public Health, 2019
Xu S, He W, Shen J, Degefu DM, Yuan L, Kong Y.   +5 more
europepmc   +1 more source

Disrupted TFEB/GDNF–cAMP/ATP Coupling Underlies Astrocytic Dysfunction and Depression in LRRK2 G2019S Parkinson's Mice

Advanced Science, EarlyView.
ABSTRACT The LRRK2 G2019S mutation, a Parkinson's disease–linked variant, has been associated with depression‐like phenotypes, but mechanisms remain unclear. We chart age‐dependent behavioral changes and astrocyte reactivity in G2019S mice and define a pathway connecting LRRK2 to TFEB/GDNF signaling, cellular energetics, and inflammation.
Longping Yao, Maryam Hatami, Sumeyye Koc, Qing Jiang, Thomas Skutella, Yuanfeng Zhang   +5 more
wiley   +1 more source

Assessment of the water-energy-food nexus in the life cycle of energy products. [PDF]

Heliyon
Kock S, Piastrellini R, Arena AP.
europepmc   +1 more source

The Water-Energy-Food Nexus as a Tool to Transform Rural Livelihoods and Well-Being in Southern Africa. [PDF]

Int J Environ Res Public Health, 2019
Mabhaudhi T, Nhamo L, Mpandeli S, Nhemachena C, Senzanje A, Sobratee N, Chivenge PP, Slotow R, Naidoo D, Liphadzi S, Modi AT.   +10 more
europepmc   +1 more source

UDP‐Glucose‐6‐Dehydrogenase Mediated O‐GlcNAcylation of Tight Junction Protein 1 Suppresses Metastasis in Renal Cell Carcinoma

Advanced Science, EarlyView.
Our research unveiled a regulatory paradigm wherein TRIM25 orchestrates the ubiquitin‐mediated degradation of UGDH. UGDH modulates the protein stability of TJP1 by regulating O‐GlcNAcylation levels, effectively impeding the metastasis of ccRCC. Our insights elevate UGDH to a pivotal biomarker and tumor suppressor, marking the first demonstration that ...
Xiaolin Chen, Yuhang Bao, Tao Liu, Jianhui Qiu, Yuanyuan Ma, Zedan Zhang, Chuandong Wang, Ruiyi Deng, Zheng Song, Tianyi He, Haode Liu, Jingcheng Zhou, Yizhou Wang, Kan Gong   +13 more
wiley   +1 more source

Climate Change Adaptation through the Water-Energy-Food Nexus in Southern Africa. [PDF]

Int J Environ Res Public Health, 2018
Mpandeli S, Naidoo D, Mabhaudhi T, Nhemachena C, Nhamo L, Liphadzi S, Hlahla S, Modi AT.   +7 more
europepmc   +1 more source

TOLLIP Inhibits Psoriasis Progression via Suppressing PKM2‐Mediated Glycolysis in Keratinocytes

Advanced Science, EarlyView.
In this study, we identify TOLLIP as a critical regulator of psoriasis pathogenesis through its modulation of glycolytic metabolism. Our findings establish the TOLLIP‐PKM2‐glycolysis axis as a key mechanism linking metabolic reprogramming to psoriasis pathogenesis, and propose TOLLIP as a promising therapeutic target.
Xiuhuan Jiang, Guoying Miao, Na Shen, Qingxia Han, Xiaoru Han, Zichang Qiao, Kexin Feng, Zhuo Tan, Yaguang Wang, Xiuhua Liu, Chen Wu, Zhenzhen Yan   +11 more
wiley   +1 more source

Toward improving water-energy-food nexus through dynamic energy management of solar powered automated irrigation system. [PDF]

Heliyon
Yadav N, Pattabiraman B, Tummuru NR, Soundharajan BS, Kasiviswanathan KS, Adeloye AJ, Sen S, Maurya M, Vijayalakshmanan S.   +8 more
europepmc   +1 more source

Empirical Framework for a Relative Sustainability Evaluation of Urbanization on the Water⁻Energy⁻Food Nexus Using Simultaneous Equation Analysis. [PDF]

Int J Environ Res Public Health, 2019
Fan C, Lin CY, Hu MC.
europepmc   +1 more source