Results 71 to 80 of about 12,493,917 (291)

MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation

FEBS Open Bio, EarlyView.
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima, Kotone Watanabe, Grigorii Sultanakhmetov, Aoi Fukuchi, Keiya Ito, Sawako Shimizu, Taro Saito, Akiko Asada, Kanae Ando   +8 more
wiley   +1 more source

Water–energy–food–ecosystem nexus: how to frame and how to govern

Sustainability Science
Abstract The food, energy, and water domains are strongly interrelated. The body of literature investigating these interlinkages developed into water–energy–food and, more recently, ecosystem (WEFE) nexus thinking. The WEFE nexus is concerned with cross-sectoral resource management requiring dedicated WEFE governance approaches. Among
Mooren, Caro Eline, Munaretto, Stefania, La Jeunesse, Isabelle, Sievers, Eva, Hegger, Dries Leonardus Theodora, Driessen, Petrus Paulus Joseph, Hüesker, Frank, Cirelli, Claudia, Canovas, Ingrid, Mounir, Kaoutar, Madrigal, Jonatan Godinez   +10 more
openaire   +4 more sources

Fluorination: A strategy to tune the interactions of molecules and nanoscale systems with biological matter

FEBS Open Bio, EarlyView.
This minireview explores fluorination as a key strategy to optimize therapeutic molecules and nanocarriers. By incorporating different fluorinated motifs—from single atoms to linear and branched chains—drug delivery, cellular uptake, and colloidal stability can be improved and fine‐tuned.
Martina Beccalli, Beatrice Lucia Bona, Francesca Baldelli Bombelli   +2 more
wiley   +1 more source

Energy-Water-Food-Environment Nexus and Circular Economy: A Systematic Review [PDF]

E3S Web of Conferences
The increasing demand for essential resources such as water, food, and energy will hurt the environment. Nexus thinking emerges as a way of thinking about the interdependence of multiple resource flows within a specific temporal and spatial context, such
Nugraha Nurmuntaha Agung, Pudyastuti Purwanti Sri   +1 more
doaj   +1 more source

Simulation Study on the Different Policies of Jiangsu Province for a Dynamic Balance of Water Resources under the Water–Energy–Food Nexus

, 2020
In order to promote the efficient use of resources and the sustainable development of the economy in Jiangsu Province, it is particularly important to ease the contradiction between water supply and demand on the basis of realizing the coordinated ...
Weizhong Chen, Yan Chen
core   +1 more source

Pain and Patient‐Reported Physical Function Did Not Differ Among Body Composition Profiles in Patients With Hip Osteoarthritis

Arthritis Care &Research, EarlyView.
Objective To explore whether higher body fat and lower lean mass are associated with greater pain and worse patient‐reported physical function in individuals with hip osteoarthritis (OA). A secondary aim was to examine whether pain and patient‐reported physical function differ according to four body composition profiles: high body fat, low lean mass ...
Alexandra Ryan, Boliang Wang, Fiona Dobson, Ben Kirk, Travis Haber, Kim L. Bennell, Shirley P. Yu, Kim Allison, Ricardo J. S. Costa, Gabrielle Knox, Michelle Hall   +10 more
wiley   +1 more source

Water-Energy-Food Nexus

, 2018
This article was developed as an outcome of the “Water-Energy-Food Nexus” High Level Panel (HLP) which took place at the XVI World Water Congress, Cancun Mexico, June 1, 2017. The HLP’s goal was to demonstrate the extent of interconnection between the water, energy, and food Sustainable Development Goals (SDGs) of the United Nations.
Stephan, Raya, Mohtar, Rabi H., Daher, Bassel, Embid, Antonio, Hillers, Astrid, Ganter, Carl, Karlberg, Louise, Martin, Liber, Nairiz, Saeed, Rodriguez, Diego J., Sarni, Will   +10 more
openaire   +1 more source

Distribution Characteristics, Regional Differences and Spatial Convergence of the Water-Energy-Land-Food Nexus: A Case Study of China

, 2022
Land use change affects the supply and demand of water, energy and food and the integration of land elements into the common water-energy-food (WEF) nexus, which is an effective way to strictly adhere to the bottom line of natural resources.
Qiangyi Li, Chenyang Guo, Fangxin Jiang, Shuya Han, Yangqing Liu, Lan Yang   +5 more
core   +1 more source

Food System and Water–Energy–Biodiversity Nexus in Nepal: A Review

Agronomy, 2020
Water, energy, and biodiversity are essential components for building a sustainable food system in a developing country like Nepal. Green Revolution technologies and the package of practices largely ignored the role of ecosystem services, leaving a large
Roshan Subedi, Madhav Karki, Dinesh Panday   +2 more
doaj   +1 more source

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

Advanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio, B. Spedicato, G. Corallo, A. Inguscio, M. Greco, D. Musarò, D. Vergara, A. F. Muro, G. De Sabbata, L. R. Soria, N. Brunetti Pierri, M. Maffia   +11 more
wiley   +1 more source