Results 51 to 60 of about 13,840,677 (308)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Scientific ReportsThe Notch1 signaling pathway plays a crucial role in the development of the central nervous system, governing pivotal functional activities in the brain, such as neurogenesis.
Atefeh Mohammadi +2 more
doaj +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Application of principal component analysis in well water research for human consumption [PDF]
Población y Desarrollo, 2017 The adverse effect of organic waste on the quality of groundwater can be a serious problem for human health. The objective of this study was to evaluate the contamination with nitrites, nitrates and coliform bacteria in groundwater samples in the rural ...
Juan Gustavo Rodríguez +1 more
doaj +1 more source
An Evaluation of the Effects of Dredging Within the Arkansas River Navigation System - Volume I - Introduction, Summary and Conclusions, and Recommendations [PDF]
, 1978 The foundation for the development of the Arkansas River was laid with the authorization of many upstream reservoirs in the comprehensive River and Harbor Act of 1946 signed by President Truman.
Research Center, Arkansas Water Resources
core +2 more sources
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
BMC Global and Public HealthStrengthening midwifery education and the quality of midwifery care is one of the most impactful interventions to address maternal and newborn morbidity and mortality.
Brittney J. van de Water, Julie Mann
doaj +1 more source
Potential of condensate as a water source from air conditioning systems: A thermodynamic analysis [PDF]
Journal of Applied Research in Water and WastewaterA considerable amount of water condensate produced through the cooling coils of air conditioning systems is usually directed to municipal sewage systems and wasted along with the energy it contains.
Koorosh Goudarzi
doaj +1 more source
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
Influence of temperature on the volumetric properties of ethanol + water + 1pentanol [PDF]
Journal of the Serbian Chemical Society, 2004 Knowledge of physical properties and phase equilibria is necessary for the design and optimization of the equipment for the production of distilled alcoholic beverages.
M. IGLESIAS +3 more
doaj